The incidence, pathophysiology, provoking factors, and recommended treatments for several types of unusual thrombosis were summarized in a review article.
Patients With Splanchnic Vein Thrombosis May Have Increased Risk of Bleeding and Arterial Cardiovascular Events
Researchers analyzed 1915 patients with splanchnic vein thrombosis for risk of bleeding and arterial cardiovascular events.
Researchers performed a retrospective review of 1279 patients treated with a standardized, weight-adjusted tinzaparin regimen.
Direct-Acting Oral Anticoagulants May Be Efficacious in Treating Cancer-Associated Venous Thrombosis
Researchers evaluated 12 studies including 4720 patients for recurrent VTE risk and major bleeding.
Prophylactic rituximab may decrease relapse in immune thrombotic thrombocytopenic purpura by maintaining detectable levels of ADAMTS13 activity.
Patients with pregnancy-onset ITP were more likely to deliver babies with neonatal thrombocytopenia compared with patients diagnosed before pregnancy.
Patients with VTE with moderate to severe thrombocytopenia at baseline were associated with increased risk for major bleeding events and all-cause mortality.
Forty-three percent of patients on fostamatinib and 14% on placebo achieved overall responses (defined as ≥1 platelet count ≥50,000/μL within the first 12 weeks on treatment).
A number of risk factors were associated with chronic thromboembolic pulmonary hypertension, including, age >70 years, female gender, and pulmonary embolism at first venous thromboembolism.
Perioperative red blood cell transfusion linked to increased adjusted odds of venous thromboembolism, deep vein thrombosis, and pulmonary embolism.
At the end of 6 months, the rate of VTE recurrence was 4% among rivaroxaban patients vs 11% in the dalteparin arm (hazard ratio [HR] 0.43, 95% CI: 0.19 to 0.99).
D-dimer test adjustment based on pretest probability results may be a safe option to reduce the need for imaging during evaluation for pulmonary embolism.
The Society of Radiologists in Ultrasound has endorsed recommendations regarding ultrasound imaging test protocols for patients with suspected deep venous thrombosis.