Female Patients With Bleeding Disorders Included in the American Thrombosis and Hemostasis Network Dataset
The most common bleeding disorder in this cohort was von Willebrand disease, which comprised 62.9% of diagnoses.
Von Willebrand Disease
Lack of Standardized Treatment for Pregnant Women With Type 3 von Willebrand Disease
Researchers conducted a systematic review to assess outcomes and complications in pregnant women with type 3 von Willebrand disease.
Acquired von Willebrand Syndrome in Pediatric Patients With Chronic Myeloid Leukemia
Researchers assessed whether high platelet counts in pediatric patients with chronic myeloid leukemia resulted in thrombosis or bleeding.
Children With Type 3 von Willebrand Disease More Likely To Report Bleeds, Need for Mobility Assistance
Male patients with von Willebrand disease were more likely to be diagnosed earlier and to report bleeds compared with female patients.
Advances in the Diagnosis of Type 1 von Willebrand Disease: Genetic Testing
Despite the increasing availability of gene sequencing, several barriers prevent it from having utility as a tool for diagnosis of type 1 von Willebrand disease.
Initial Laboratory Testing Sufficient for Diagnosing von Willebrand Disease in Many Pediatric Patients
For a cutoff von Willebrand factor antigen value of 100 IU/dL above which repeat testing was not necessary, negative predictive value was 96.6%.
Challenges in Diagnosing and Managing von Willebrand Disease
Researchers highlighted the current status of diagnostic strategies and laboratory screening tests for von Willebrand disease.
Prevalence of Gastrointestinal Bleeding in Patients With von Willebrand Disease
Researchers conducted a retrospective analysis of records from the National Inpatient Sample to identify risk factors for gastrointestinal bleeding.
Body Mass Index Associated With Increased von Willebrand Factor, Factor VIII Levels
For both type 1 and type 2 von Willebrand disease, higher BMI was associated with increased VWF:Ag and FVIII:C levels.
The Role of Cardiovascular Diseases in the Pathogenesis of Acquired von Willebrand Syndrome
High shear stress in blood vessels due to cardiovascular disease may be associated with the development of acquired von Willebrand syndrome.
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