von Willebrand Disease: Recent Developments in Diagnosis, Treatments
New developments in lab assays have allowed for more specialized assessments of VWD activity, leading to better diagnoses and various treatment options.
Von Willebrand Disease
von Willebrand Disease False Levels, Misdiagnosis Still an Issue With Off-Site Testing
The percentage of discordance in onsite and off-site laboratory testing of von Willebrand disease remains high.
Patterns of Type 2 von Willebrand Disease in Patients in Iran
Researchers assessed 136 patients with VWD in Iran over 13 years to characterize clinical and molecular patterns associated with the disease.
Female Patients With Bleeding Disorders Included in the American Thrombosis and Hemostasis Network Dataset
The most common bleeding disorder in this cohort was von Willebrand disease, which comprised 62.9% of diagnoses.
Lack of Standardized Treatment for Pregnant Women With Type 3 von Willebrand Disease
Researchers conducted a systematic review to assess outcomes and complications in pregnant women with type 3 von Willebrand disease.
Acquired von Willebrand Syndrome in Pediatric Patients With Chronic Myeloid Leukemia
Researchers assessed whether high platelet counts in pediatric patients with chronic myeloid leukemia resulted in thrombosis or bleeding.
Children With Type 3 von Willebrand Disease More Likely To Report Bleeds, Need for Mobility Assistance
Male patients with von Willebrand disease were more likely to be diagnosed earlier and to report bleeds compared with female patients.
Advances in the Diagnosis of Type 1 von Willebrand Disease: Genetic Testing
Despite the increasing availability of gene sequencing, several barriers prevent it from having utility as a tool for diagnosis of type 1 von Willebrand disease.
Initial Laboratory Testing Sufficient for Diagnosing von Willebrand Disease in Many Pediatric Patients
For a cutoff von Willebrand factor antigen value of 100 IU/dL above which repeat testing was not necessary, negative predictive value was 96.6%.
Challenges in Diagnosing and Managing von Willebrand Disease
Researchers highlighted the current status of diagnostic strategies and laboratory screening tests for von Willebrand disease.
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