Cyclophosphamide in Treatment of Immune Thrombotic Thrombocytopenic Purpura
A retrospective analysis showed similar outcomes for cyclophosphamide as seen with rituximab in treatment of immune thrombotic thrombocytopenic purpura.
Thrombotic Thrombocytopenic Purpura
Real-World Study of Caplacizumab for Thrombotic Thrombocytopenic Purpura
A retrospective analysis shows that real-world outcomes with caplacizumab for thrombotic thrombocytopenic purpura are similar to clinical trial results.
Thrombotic Thrombocytopenic Purpura: Triplet Therapy May Prevent Unfavorable Outcomes
Caplacizumab with therapeutic plasma exchange and immunosuppression appears to prevent unfavorable clinical outcomes in patients with immune-mediated TTP.
Treatment of Thrombotic Thrombocytopenic Purpura in Pregnancy
A pair of researchers discuss the treatment and specific clinical challenges associated with thrombotic thrombocytopenic purpura in women who are pregnant.
Elevated Plasma Syndecan-1, Thrombomodulin Linked to Exacerbated Immune-Mediated Thrombotic Thrombocytopenic Purpura
Hospitalized patients with elevated Sdc-1 levels have a higher risk for death in patients with iTTP. Levels may be used for risk stratification.
Screening for Gaucher Disease in Canadian Patients With Thrombocytopenia
A single-center study in Canada found a point prevalence of Gaucher disease of 0.5% among Canadian patients referred to a hematologist for thrombocytopenia.
Acute Thrombotic Thrombocytopenic Purpura: Abnormal MRI Linked to Cognitive Impairment
Cerebral MRI data suggest that neurological symptoms and cognitive impairment may be common among patients with an acute TTP event.
Outcomes of Systemic Lupus Erythematosus in Immune-Mediated Thrombotic Thrombocytopenic Purpura
Thrombotic thrombocytopenic purpura (TTP) related to systemic lupus erythematosus may not cause worse outcomes compared with primary immune-mediated TTP.
Level of Health Literacy Among Patients With Thrombotic Thrombocytopenic Purpura
A team of investigators evaluated knowledge gaps among patients with TTP in remission and found a range of levels of understanding of the condition.
Thrombotic Thrombocytopenic Purpura: Expert Recommendations, Good Practice Statements for Critical Care
TTP is a rare disease that clinicians may not often treat; however, it is important to be aware of new developments for the treatment of this patient population.
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