Early Recognition Important for Implementing Interventions in Patients With Hereditary Thrombotic Thrombocytopenic Purpura
Researchers sought to determine the state of detection and initiation of prophylactic treatment for patients with hTTP.
Researchers sought to determine the state of detection and initiation of prophylactic treatment for patients with hTTP.
Researchers sought to improve outcomes for pregnant patients with cTTP using prophylactic FFP.
Hemoglobin levels, platelet counts, creatinine levels, and ADAMTS13 activity were all significantly higher in the general TMA group.
Researchers attempted to revise clinically relevant definitions for patients with iTTP in light of recent changes.
A novel assay for evaluating ADAMTS13 activity may be both fast and reliable for the diagnosis of thrombotic thrombocytopenic purpura (TTP), according to the results of a study published in Research and Practice in Thrombosis and Hemostasis. A thrombotic microangiopathy that can be life-threatening, TTP can be diagnosed only through measurement of ADAMTS13 activity, which…
A single-institution chart review of patients with TTP showed evidence that they may be at higher risk for VTE; therefore, there may be a need to implement VTE thromboprophylaxis earlier for hospitalized patients.
A letter to the editor drew attention to the increased risk of thrombotic disorder for patients with severe COVID-19, which seems to occur by interacting with the von Willebrand Factor-ADAMTS13 axis.
A team of researchers sought to determine the frequency of and risk factors associated with ischemic stroke in patients with immune thrombotic thrombocytopenic purpura.
Researchers identified predictive markers — including plasma levels of S100A8/A9, histone/DNA complexes, and cell-free DNA — for the pathogenesis of and prognosis for patients with iTTP.
A 2-fold increase in mortality was seen among patients with thrombotic thrombocytopenic purpura compared with the general US population.