Risk Factors for Recurrent Venous Thromboembolism in Patients With Sickle Cell Disease
Patients with severe sickle cell disease were more than twice as likely to experience recurrent thromboembolism compared with patients with less severe disease.
Thromboembolism
VTE-BLEED Risk Score Reliably Identifies Patients With PE at Risk for Major Bleeding
The VTE-BLEED risk score identified patients with pulmonary embolism at risk for in-hospital major
bleeding.
Novel Reversal Agent for Ticagrelor Gets FDA’s Breakthrough Tx Designation
The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to PB2452 (PhaseBio), an investigational reversal agent for ticagrelor.
Direct-Acting Oral Anticoagulant Treatment for Acute Venous Thromboembolism
Although clinical trials are ongoing, the safety profile and net clinical benefit of DOACs for acute venous thromboembolism treatment are unclear.
Optimal Approaches to Treating Venous Thromboembolism in Patients With Cancer
Recent studies suggest that direct-acting oral anticoagulants may be a viable treatment option for cancer patients with VTE, but more research is needed.
Apixaban May Reduce Risk for Venous Thromboembolism in Patients With Cancer
Significantly fewer patients receiving apixaban experienced thromboembolism and major bleeding compared with patients receiving placebo.
No Association Found Between Locations of Venous Thromboembolism and Occult Cancer
An analysis of 2300 patients found similar prevalence of abdominal, pelvic, and thoracic cancer in patients with deep vein thrombosis and pulmonary embolism.
Managing Venous Thromboembolism in Transgender Women Receiving Hormone Therapy
Transgender women receiving hormone replacement therapy may be at an increased risk for thromboembolism, though data and recommendations vary across studies.
Lack of Thromboprophylactic Benefit With Rivaroxaban in Ambulatory Patients With Cancer
Patients receiving rivaroxaban did not experience a statistically significant decrease in thrombotic events compared with patients receiving placebo.
Novel Risk Factors for Venous Thromboembolism in Pregnancy and Postpartum
Researchers assessed potential risk factors for venous thromboembolism during pregnancy and postpartum in more than 100,000 Japanese women.
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