Review of Features, Treatment Options in Peripheral T-Cell Lymphoma
Combined targeted agents with immune regulators and chimeric antigen receptor cell–based therapies may improve overall survival for patients with PTCL.
Combined targeted agents with immune regulators and chimeric antigen receptor cell–based therapies may improve overall survival for patients with PTCL.
Researchers characterized outcomes for enteropathy-associated T-cell lymphoma, hepatosplenic T-cell lymphoma, and peripheral gamma delta T-cell lymphoma.
Antibiotic treatment with carbapenem for S. aureus infection was efficacious in patients with cutaneous T-cell lymphomas.
Current guidelines support autologous transplantation for consolidation in transplant-eligible patients with peripheral T-cell lymphoma.
Patients with higher International Prognostic Index scores or advanced-stage disease experienced improved survival when treated with ASCT.
Changes to the WHO-EORTC classification for primary cutaneous lymphomas were highlighted in a recent review article.
The approval was based on data from a randomized, double-blind, double-dummy, actively controlled trial (ECHELON-2) involving 452 patients with certain PTCLs.
Though the majority of patients with cutaneous T cell lymphomas experience pruritus, the pathophysiology of the symptom is relatively unclear.
Patients with peripheral T-cell lymphomas have a median overall survival of approximately 6 months.
Previous study suggests that EFS is a prognostically relevant variable among patients with other lymphomas; for this study, researchers evaluated whether EFS24 predicts for overall survival in PTCL.