Screening for Social Determinants of Health to Improve Care for Pediatric Sickle Cell Disease
Approximately two-thirds of patients who completed a screening questionnaire reported having at least 1 unmet socioeconomic need.
Sickle Cell Disease
Incidence of Ischemic Stroke in Patients With Sickle Cell Disease on the STOP Protocol
Nearly two-thirds of ischemic strokes occurred in patients who had not properly completed the STOP protocol.
Missed Clinic Appointments Predictive of Hospital Admission and Readmission in Sickle Cell Disease
Depressive symptoms, spirituality, and missed clinic appointments were all found to correlate with hospital admission in sickle cell disease.
Study Investigating Rivipansel in Patients With Sickle Cell Disease Misses End Points
The primary end point was time to readiness for discharge, defined as the difference between the readiness-for-discharge date and time and the start date and time of the first infusion of study drug.
Crizanlizumab Granted Priority Review for Sickle Cell Pain Crises Prevention
Priority Review shortens the FDA review time from 10 months to 6 months
Hospital Admission Rates in Children With Sickle Cell Disease Seeking Pain Management
Patients presenting at emergency departments were nearly 4 times as likely to be admitted to a hospital as patients presenting at a day hospital.
Pharmacokinetic-Guided Hydroxyurea Dosing Beneficial for Very Young Children With Sickle Cell Disease
Young patients with sickle cell disease underwent dosing schedules guided by analysis of pharmacokinetic data using a population pharmacokinetic model.
Response to Voxelotor in Phase 3 Trial for Sickle Cell Disease
Voxelotor may be a safe and efficacious treatment for sickle cell disease, especially at a dosage of 1500 mg/d.
Risk Factors for Recurrent Venous Thromboembolism in Patients With Sickle Cell Disease
Patients with severe sickle cell disease were more than twice as likely to experience recurrent thromboembolism compared with patients with less severe disease.
Individualized Management Approach May Improve Care and Cut Costs for Sickle Cell Pain
A multidisciplinary intervention strategy led to a 61% decrease in hospital stay duration for patients with sickle cell disease and vaso-occlusive pain.
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