Alpha-1-Microglobulin and Acute Kidney Injury Associated With Sickle Cell Disease
A special commentary article explained that acute kidney injury can be a complication of vaso-occlusive episodes associated with sickle cell disease.
Sickle Cell Disease
Bleeding Incidences in Patients With Sickle Cell Disease
The authors included 6423 patients with SCD in what is believed to be the first study of the incidence of bleeding events in this patient population.
Improved Neurocognitive Function With Hydroxycarbamide in Adolescents With Sickle Cell Disease
Patients who received hydroxycarbamide therapy scored higher on several measures of neurocognition compared to patients who did not receive hydroxycarbamide.
Vitamin D Deficiency and Hospital-Related Outcomes for Patients With Sickle Cell Disease
Patients with sickle cell disease and vitamin D deficiency reported higher rates of emergency room visits and hospital admissions for pain crises.
New ASH Clinical Guidelines on Transfusion Support for Sickle Cell Disease
A panel of researchers developed evidence-based guidelines to support clinical decision making regarding transfusion support for patients with sickle cell disease.
Endurance Exercise Improves Skeletal Muscle Microvasculature in Patients With Sickle Cell Disease
Patients who underwent moderate-intensity endurance training experienced improvements in capillary density and number of capillaries around a fiber.
Cell Therapy Transplant Approach Holds Early Promise for Patients With Sickle Cell Disease
Researchers assessed a method of extracting marrow cells and transforming them to promote fetal hemoglobin generation in patients with sickle cell disease.
Clinician Attitudes About Discussing Hematopoietic Cell Transplantation for Sickle Cell Disease
Clinicians reported informing only 42% of families about hematopoietic cell transplantation, citing concerns about safety and cost.
Adakveo Approved for Sickle Cell Disease
The FDA has approved Adakveo (crizanlizumab-tmca; Novartis) to reduce the frequency of vaso-occlusive crisis (VOC) in patients aged ≥16 years with sickle cell disease.
Modeling Lost Income and Life Expectancy Due to Sickle Cell Disease
Individuals with sickle cell disease were estimated to earn nearly $700,000 less over their lifetime compared with similar individuals without sickle cell disease.
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