Sickle Cell Disease

Quantitative sensory testing may facilitate objective evaluation of feelings of pain and function in patients with sickle cell disease.

Mometasone usage was found to correlate with decreased levels of macrophage markers but not of asthma-related markers.

Infants with sickle cell disease who started hydroxyurea before 12 months of age had better long-term outcomes.

A set of diagnostic criteria for defining the types of acute pain observed in patients with sickle cell disease was formulated by a multi-institutional panel of experts.

The use of a less toxic conditioning regimen may establish bone marrow transplantation as a preferred therapeutic alternative for adults with sickle cell disease.

Researchers assessed 266 pregnant women with and without sickle cell disease in Ghana to determine the effect of a multidisciplinary care strategy.

Investigators conducted a systematic review of 7083 studies to evaluate the association between sickle cell trait and any of 24 adverse clinical outcomes.