A New Era in Awareness for Sickle Cell Disease Testing in the Caribbean
Researchers in the Caribbean are seeking to make strides in care and testing for patients with sickle cell disease.
Diagnosis & Disease Information
Genome-Edited Product May Attenuate Sickle Cell Disease
Researchers sought to determine whether genome-edited autologous OTQ923 would lead to production of red-cell fetal hemoglobin and clinical improvement in SCD.
Managing Acute Vaso-Occlusive Crises in Sickle Cell Disease
Researchers have sought to determine better ways to manage patients with SCD experiencing pain or a vaso-occlusive sickle cell crisis.
Sex, Healthcare Utilization for Acute Pain Associated With Hospitalization Among Adolescents With SCD
Researchers sought to determine whether there is a link between patient sex and HCU for acute pain trajectories in adolescents with SCD.
Pain and Fatigue Not Linked With Neurocognitive Function SCD
Researchers sought to determine whether there is a link between pain or fatigue and neurocognitive function in patients with SCD.
Improving Hemoglobin Levels May Lead to Improved Neurocognition and Educational Outcomes Among Children With SCD
Researchers sought to determine whether improving hemoglobin levels in children with SCD would improve neurocognition and educational outcomes.
Zinc Supplementation Does Not Reduce Severe Infection Rates Among Children With SCD
Researchers sought to determine whether zinc supplementation would reduce incidence of severe or invasive infections in children with SCD.
Untangling the Determinants of Pain in Sickle Cell Disease
Researchers sought to determine the manifestations of sickle cell disease that are associated with pain and poor quality of life.
Sickle Cell Disease Highly Contributes to All-Cause Mortality
Global sickle cell disease mortality burden was 376,000 in 2021; 81,100 deaths reported in children younger than 5 years.
Free Heme Impairs Macrophage Function and Exacerbates Tissue Damage in Sickle Cell Disease
Researchers sought to determine the impact of free heme associated with hemolysis on tissue damage in patients with sickle cell disease.
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