Lenalidomide May Select for TP53-Mutated Clones, Increasing Risk of Therapy-Related MNs
Researchers sought to determine the role of lenalidomide in the pathogenesis of therapy-related myeloid neoplasms.
Myeloproliferative Neoplasms
Endoscopic Procedures Improve Gastroesophageal Variceal Rebleeding in MPN
Researchers sought to determine the efficacy of endoscopic management of recurrent GVB in patients with MPN.
Risk Factors Identified for Secondary Myeloid Neoplasms in Aplastic Anemia, PNH
Researchers sought to determine risk factors for developing secondary myeloid neoplasm in patients with severe aplastic anemia.
Risk of Arterial Thrombosis Higher With COVID-19 in Patients With Myeloproliferative Neoplasms
Researchers sought to determine whether there was a higher risk of developing thrombosis in patients with MPNs and COVID-19.
Pemazyre Approved for Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement
The approval was based on data from the phase 2 FIGHT-203 study, which included 28 patients with relapsed or refractory myeloid/lymphoid neoplasms with FGFR1 rearrangement.
Certain Blood Cancer Patients Do Not Seroconvert After a Third COVID-19 Vaccine Dose
Seroconversion rates were low for patients receiving anti-CD20 therapy, CAR T-cell therapy, and transplants, as well as CLL patients taking ibrutinib.
Study Advances Knowledge Base About Children and Adolescents With Myeloproliferative Neoplasms
The researchers uncovered higher-than-anticipated rates of thrombosis, hemorrhage, and transformation in their real-world cohort of MPN patients.
Differences in Cytopenia in MDS May Be Related to Genetic Mutations
Researchers sought to determine whether there were differences in cytopenia and other factors in patients with MDS or MPN.
Cancer Guidelines May Ease Disease-Specific Fatigue in Patients With Myeloproliferative Neoplasm
A qualitative study sought to define the symptoms patients with MPN-related fatigue experience.
SARS-CoV-2 Vaccination Reduces Risk of Mortality and Hospitalization in MPNs
A single-center study sought to determine the effects of SARS-CoV-2 vaccination in patients with myeloproliferative neoplasms.
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