Geno-Clinical Decision Model Accurately Predicts Diagnosis of Myelodysplastic Syndrome
Researchers sought to determine whether a machine learning-based model would be able to accurately predict the diagnoses of myeloid malignancies.
Myelodysplastic Syndromes
Nonablative Chemotherapy Paired With Novel T-Cell Therapy Appears Safe and Effective in Older Patients With AML and MDS
Researchers sought to determine whether nonablative chemotherapy followed by HLA-mismatched allogeneic T-cell infusion would be safe and effective in older patients with AML or MDS.
PARP1 Represents a Promising Therapeutic Target in Acute Myeloid Leukemia and Myelodysplastic Syndrome
Researchers sought to determine the role of PARP1 in the physiological and pathological effects in MDS and AML.
Treatment With Azacitidine, Lenalidomide and Donor Lymphocyte Infusion in Myeloid Malignancies After Relapse Following Allo-SCT
Patients received up to 8 cycles of AZA and up to 3 cycle of DLI with increasing T cell dosages.
Adding Pevonedistat to Azacitidine Does Not Improve Outcomes for Patients With MDS/CMML and AML
Researchers sought to determine whether adding pevonedistat to azacitidine would improve outcomes for patients with higher-risk MDS, CMML, or AML.
Features of TERT Rare Variants in Patients With Myelodysplastic Syndrome
Researchers sought to determine the effects of TERT rare variants in patients with myelodysplastic syndrome.
Predicting Post-Transplant Disease Progression in Myelodysplastic Syndrome
Researchers sought to determine whether detecting MRD with mutational analysis and FCM may aid in predicting disease progression following myeloablative allo-HSCT in patients with MDS.
Allogeneic Hematopoietic Stem Cell Transplantation Negates Poor Outcomes in Myelodysplastic Syndrome With Myelofibrosis
Researchers sought to determine whether allo-HSCT would negate poorer outcomes in patients with MDS who have myelofibrosis.
Safety of a Bispecific Antibody in Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome
Researchers sought to determine whether APVO436 would have a favorable safety profile in treating patients with relapsed/refractory AML or MDS.
Role of Bone Marrow Microenvironment in Myelodysplastic Syndromes
Researchers sought to determine how the bone marrow microenvironment contributes to the etiology of myelodysplastic syndrome.
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