Hemophilia Archives - Hematology Advisor

Hemophilia

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Inhibitor Development Is Rare After 75 Days of Exposure to Factor VIII in Severe Hemophilia A

In previously untreated patients with severe hemophilia A, nearly all inhibitory antibodies (inhibitors) against factor VIII develop within 75 days of exposure, according to research published in Blood. Researchers followed 1038 previously untreated pediatric patients with severe hemophilia A who received treatment with factor VIII. Median age of the cohort at first exposure was 1.1…

Researchers developed a new method to measure single cell red blood cell deformability.

Once-Weekly Prophylaxis for Low-Bleeding Patients With Severe Hemophilia A

Once-weekly prophylactic injection of glycopegylated recombinant factor VIII (N8‐GP) for severe hemophilia A appears to be efficacious and safe, according to results from the pathfinder 2 extension phase. The study, published in Haemophilia, included patients aged 12 years or older with severe hemophilia A who had experienced up to 2 bleeds during the pathfinder 2…

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