Diagnostic Approach to Severe Reactive Hemophagocytic Lymphohistiocytosis
Researchers devised a comprehensive diagnostic approach to evaluating severe reactive hemophagocytic lymphohistiocytosis.
Researchers devised a comprehensive diagnostic approach to evaluating severe reactive hemophagocytic lymphohistiocytosis.
In a large prospective study, investigators assessed whether pretransplant analyses could prevent unnecessary HSCT in children with HLH.
Although emapalumab is an effective treatment for primary hemophagocytic lymphohistiocytosis (HLH), further research is needed for secondary forms of HLH.
Emapalumab as a target therapy may benefit children with primary HLH.
Although pediatric patients with malignancy-associated HLH may have low mortality rates, they may subsequently die from underlying conditions from the malignant disease.
After defining mortality-related parameters in HLH, investigators noted that mortality rates were still high for patients with primary immunodeficiency.
Investigators aimed to characterize HLH in patients with moderate-to-severe inflammatory bowel disease.
The use of soluble interleukin-2 receptor level as a diagnostic test for secondary HLH in adults may be flawed.