Quality of Life With Busulfan and Fludarabine Compared With Busulfan and Cyclophosphamide
Patients with acute myeloid leukemia and myelodysplastic syndromes reported similar quality of life irrespective of the conditioning regimen the received.
Hematopoietic Stem Cell Transplantation
Triple-Drug Induction Therapy Yields Sustained Responses in Multiple Myeloma
Patients receiving the 3-drug treatment experienced increasing rates of complete response and measurable residual disease from induction through consolidation.
Outcomes After Delaying Hematopoietic Stem Cell Transplantation in Children With Viral Respiratory Infections
Patients with viral respiratory infections exhibited poorer outcomes following transplantation compared with patients without infection.
Barriers to Patient Access to Allogeneic Hematopoietic Stem Cell Transplantation
Poverty was associated with lower rates of allogeneic hematopoietic stem cell transplantation, even after adjusting for race and rural residency.
Outcomes Based on HSCT Conditioning Regimen for Patients With Myelodysplastic Syndromes
Nonmyeloablative conditioning was associated with increased nonrelapse mortality and shorter overall survival compared with reduced-intensity conditioning.
No Benefit With Upfront Rituximab and Autologous HSCT Consolidation for Aggressive Non-Hodgkin Lymphomas
Researchers conducted a meta-analysis of studies evaluating survival outcomes with rituximab plus chemotherapy with or without autologous HSCT.
Therapy With Sirolimus Could Prevent Graft-Versus-Host Disease After Stem Cell Transplant
Cumulative incidence of acute graft-versus-host disease within 100 days of transplant was 26% in the sirolimus group and 52% in the control group.
Relapsed Follicular Lymphoma: Stem Cell Transplantation in the Era of Targeted Therapies
Both autologous and allogeneic stem cell transplantation have shown benefits in patients with relapsed follicular lymphoma, but long-term data are lacking.
Prognostic Factors After Second Allogeneic HSCT in Patients With Relapsed Myelodysplastic Syndrome
The rate of 5-year overall survival in patients with myelodysplastic syndrome who underwent second allogeneic hematopoietic stem cell transplantation was 25.3%.
Greater Infection Risk With Unrelated Transplant Donors in Pediatric Acute Lymphoblastic Leukemia
The increased risk for infection seen in pediatric patients receiving transplants from unrelated donors could be a result of intensified graft-versus-host disease prophylaxis.
