Greater KIAA0125 Expression Is Poor Prognostic Factor for Myelodysplastic Syndrome
Among patients with myelodysplastic syndrome, long noncoding RNA KIAA0125 may predict poorer overall survival and leukemia-free survival.
Diagnosis & Disease Information
LRF Binding Site as Potential Therapeutic Target for β-Hemoglobinopathies
Researchers have identified the binding site for LRF as a therapeutic target for β-hemoglobinopathies.
Cumulative Incidences and Risk Factors for Cerebral Arteriopathy in Pediatric Sickle Cell Disease
Researchers evaluated the cumulative incidence of intracranial and extracranial arteriopathy and associated risk factors in children with sickle cell disease.
Diminished Ovarian Reserve May Be Linked to Hydroxyurea Exposure in Sickle Cell Anemia
Investigators compared ovarian reserve and assessed clinical characteristics in young women with sickle cell anemia vs those without the condition.
Cyclic Thrombocytopenia: Diagnostic and Therapeutic Strategies for a Challenging Condition
Researchers from the Medical University of Vienna highlight diagnostic and management strategies for the treatment of cyclic thrombocytopenia.
Eculizumab Can Be Safely Discontinued in Patients With Atypical Hemolytic Uremic Syndrome
With close monitoring, the discontinuation of eculizumab is safe in the majority of patients with atypical hemolytic uremic syndrome.
Thromboelastography for Patients With Slow-Flow Vascular Abnormalities
In minor procedures, coagulation differences may not be clinically significant to determine bleeding or thrombotic periprocedure complication risks.
Iron Deficiency Anemia: Vitamin C Supplementation May Not Be Necessary
For patients with iron deficiency anemia, oral iron supplementation use alone is comparable to oral supplementation with vitamin C.
Survey Suggests Patients, Physicians Aligned About Immune Thrombocytopenia Symptoms, Treatment
Survey results suggest significant alignment among patients and physicians about symptom burden of ITP, but not frequency or severity of fatigue.
Adherence to Allogeneic Stem Cell Transplantation to Improve Survival in Myelodysplastic Syndromes
With the exception of alloSCT and iron chelation therapy, many guideline treatments may not improve survival among patients with myelodysplastic syndrome.
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