Evaluation of Bleeding Events in Women and Girls With Hemophilia
A team of investigators evaluated clinical characteristics, hemostasis management, and clinical outcomes of bleeding events in women and girls with hemophilia.
Diagnosis & Disease Information
von Willebrand Factor Plasma Levels May Affect Future Venous Thromboembolism Risk
A population-based analysis suggested that plasma levels of von Willebrand factor may be a potential biomarker for the future risk of incident venous thromboembolism.
Metabolic Irregularities of Tryptophan and Serotonin Linked to Morbidity in Fanconi Anemia
A new study explores disruption of tryptophan metabolism, manifesting as dysregulation of serotonin metabolism, in patients with Fanconi anemia.
Combination Sitagliptin, Tacrolimus, Sirolimus for Prophylaxis of Acute Graft-vs-Host-Disease
Investigators aimed to determine whether DPP-4 inhibition reduces the incidence of acute graft-vs-host disease among patients receiving allogeneic HSCT.
Dexamethasone May Not Improve Outcomes in Chronic Subdural Hematoma
Treatment of symptomatic chronic subdural hematoma with dexamethasone may worsen outcomes compared with placebo.
Sitagliptin Promising Addition for Preventing Acute GVHD
Low incidence of grade 2 to 4 acute GVHD seen in patients undergoing myeloablative allogeneic hematopoietic stem cell transplantation.
Fibrinogen Concentrate for Bleeding Episodes in Pediatric Congenital Fibrinogen Deficiency
Among pediatric patients with congenital fibrinogen deficiency, the administration of human fibrinogen concentrate may be efficacious for on-demand treatment and surgical prophylaxis.
Clinical Management of Malignant Infantile Osteopetrosis
Investigators discussed their clinical approaches to the diagnosis and management of malignant infantile osteopetrosis, as well as the management of long-term posttrasnplant complications.
Higher Pretransplant Vitamin E Levels Associated With Lower Risk for Acute GVHD
Among patients receiving allogeneic stem cell transplantation, high levels of vitamin E may be linked to less acute graft-vs-host disease.
FDA Requests Clarification of Data to Complete Roxadustat Review
The Agency announced that additional clarification of clinical data was needed prior to completing the review.
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