T-Cell Subset Linked With Survival After Haplo-HCT for Acute Myeloid Leukemia
Researchers sought to determine whether greater Vδ2-positive T-cell recovery would impact mortality for patients with AML who undergo haplo-HCT.
Diagnosis & Disease Information
Persistent Organ Damage Common One Year After COVID-19
59 percent of individuals had organ impairment at one year; breathlessness, cognitive dysfunction, poor HRQoL also common.
Mega-Dose Decitabine May Improve Conditioning Before Allo-HSCT in AML
Researchers sought to determine whether a larger dose of decitabine prior to allo-HSCT would improve outcomes in patients with AML.
Orca-T Improves Allo-HSCT Outcomes Compared With Historical Control
Researchers sought to determine whether Orca-T could improve relapse and survival outcomes compared with historical controls for patients receiving allo-HSCT.
Promising Prophylactic Efficacy With RGI-2001 Plus Standard of Care for Acute GVHD
Researchers sought to determine whether adding RGI-2001 to a calcineurin inhibitor and methotrexate or mycophenolate mofetil would help prevent acute GVHD.
Calcineurin Inhibitor-Free Prophylaxis Associated With Shorter Time to Immunosuppression Withdrawal, GVHD
Researchers assessed whether PTCy with sirolimus would reduce median time to immunosuppression withdrawal and a lower rate of chronic GVHD following allo-HCT.
Itacitinib Is an Effective Treatment for Acute GVHD
Researchers sought to determine whether itacitinib would be an effective treatment for acute GVHD through a multicenter, phase 2 trial.
Ibrutinib Failed to Improve Outcomes in Previously Untreated Chronic GVHD
Researchers sought to determine whether ibrutinib could improve outcomes in the frontline setting of cGVHD.
Vitamin D Deficiency Increases Risk of Acute Graft Vs Host Disease in Thalassemia Major
Researchers sought to determine whether vitamin D deficiency before hematopoietic stem cell transplantation would impact risk of GVHD in thalassemia major.
Outcomes Superior With Peripheral Blood vs Bone Marrow Transplants in PTCL
A retrospective analysis sought to determine safety and tolerability of posttransplantation cyclophosphamide in patients with peripheral T-cell lymphoma.
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