Erythroid Differentiation Regulation Via p53 Activation During Ribosome Biogenesis
Investigators characterized ribosome biogenesis dynamics during erythropoiesis to study the role of ribosome biogenesis in normal erythroid development.
Diamond-Blackfan Anemia
Outcomes of Hematopoietic Stem Cell Transplantation in Children With Diamond-Blackfan Anemia
Children with Diamond-Blackfan anemia may benefit from HSCT when a matched sibling donor or matched unrelated donor is not available.
Clinical Profiles of Patients With Diamond-Blackfan Anemia
Using data from a nationwide registry, researchers characterized the clinical profiles of patients with Diamond-Blackfan anemia.
Evaluating Stem Cell Transplantation in Diamond-Blackfan Anemia
Patients younger than 10 years of age experienced an overall survival rate of 91% regardless of whether they received transplant from a sibling or unrelated donor.
Impaired Immunity May Be Intrinsic to Diamond-Blackfan Anemia
Decreased lymphocyte counts and serum immunoglobulin levels were seen in patients irrespective of ribosomal protein genotype and steroid treatment.
Clinical Management of Diamond-Blackfan Anemia in Children
Despite deeper understanding of some of the molecular mechanisms underlying Diamond-Blackfan anemia, the search for effective therapies is ongoing.
Patients With Diamond-Blackfan Anemia May Be at Higher Risk for Certain Cancers
Researchers analyzed prospective follow-up data from 702 patients with Diamond-Blackfan anemia for cancer incidence and risk.
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