Standard of Care More Likely to Be Cost-Effective Than CAR-T Therapy in DLBCL
Researchers sought to determine the cost-effectiveness of CAR-T therapy compared with standard of care in patients with DLBCL.
CAR-T Therapy
Cilta-Cel May Fulfill Unmet Need for Multiple Myeloma Patients in China
Ciltacabtagene autoleucel had a favorable risk-benefit profile in a study of Chinese patients with relapsed/refractory multiple myeloma, according to researchers.
FLT3-Targeted CAR-T Cells Show Antitumor Activity in KMT2A-Rearranged B-Cell Acute Lymphoblastic Leukemia
Researchers sought to determine whether FLT3-targeted CAR-T cells could have antitumor activity in patients with B-ALL with KMT2A rearrangement.
Ciltacabtagene Autoleucel Improves Health-Related Quality of Life in Relapsed/Refractory Multiple Myeloma
Researchers sought to determine whether ciltacabtagene autoleucel would result in durable responses in patients with R/R multiple myeloma.
Nonresponse to Tisagenlecleucel Associated With Poor OS in B-Cell Acute Lymphoblastic Leukemia
Researchers sought to determine whether a lack of response to tisagenlecleucel had a link with survival in patients with B-ALL.
Tisagenlecleucel Plus Pembrolizumab May Be Effective in Patients With R/R Diffuse Large B-Cell Lymphoma
Researchers sought to determine whether CAR-T therapy following pembrolizumab treatment would be effective in patients with relapsed/refractory DLBCL.
Access to Trials of CAR T-Cell Therapy or Bispecific Antibodies May Vary by Race
Black patients with multiple myeloma may not have equitable access to clinical trials of CAR T-cell therapy or bispecific antibodies.
Genomic Features and Anti-CD19 CAR-T Therapy Failure in Large B-Cell Lymphoma
Researchers sought to identify genomic features in patients with large B-cell lymphoma that are linked with anti-CD19 CAR-T therapy.
Real-World Data Suggest Tisagenlecleucel Is Effective in Infant B-ALL
Researchers sought to determine whether tisagenlecleucel was effective would be effective in infant patients with B-ALL
Coagulation Parameters With Cytokine-Release Syndrome and CAR-T Therapy in B-Cell Lymphomas
Researchers sought to determine patterns in coagulation parameters linked to cytokine-release syndrome in patients receiving CAR-T therapy.
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