Increased Risk for Hemorrhage With Aspirin Plus Anticoagulation for Polycythemia Vera
Patients receiving aspirin and anticoagulation experienced a 3-fold increase in risk for severe hemorrhage compared with patients receiving either treatment alone.
Diagnosis & Disease Information
Rivaroxaban May Be a Feasible Treatment Option for Thromboembolism in Children
Most individual pharmacokinetic parameter values fell within the expected range irrespective of dosage, VTE outcome, and bleeding events.
Relapse Delayed But Not Prevented With Rituximab for Immune TTP
Patients treated with rituximab experienced improved relapse-free survival at 1 and 3 years but not 5 years after treatment compared with patients receiving corticosteroids alone.
Neutropenia Rates Among Patients Receiving Rituximab for Nonmalignant Immune-Mediated Hematologic Diseases
Researchers found that rituximab is linked to neutropenia in fewer than 1 in 20 cases among patients with a NMIHD.
Evidence of Clinical Benefit for Bispecific Antibody in Patients With Refractory Multiple Myeloma
This dose-finding study examined a bispecific antibody targeting BCMA and CD3 in patients with R/R multiple myeloma.
Does Real-World Evidence Support Apixaban Use in Cancer-Related Venous Thromboembolism?
Researchers assessed clinical outcomes with apixaban, low-molecular-weight heparin, and warfarin to treat venous thromboembolism in patients with cancer.
High Rates of Undetectable MRD Following 2 Years of Ibrutinib-Venetoclax in Certain Patients With CLL/SLL
There is an increasing focus on using the achievement of undetectable MRD in bone marrow as a clinical trial end point in patients with CLL.
Promising First-Line Immunotherapy Findings in Hodgkin Lymphoma: Complete Response of 100%
The study yielded a complete response rate of 100% across 33 subjects.
Evaluating Stem Cell Transplantation in Diamond-Blackfan Anemia
Patients younger than 10 years of age experienced an overall survival rate of 91% regardless of whether they received transplant from a sibling or unrelated donor.
Characterizing Intracranial Hemorrhage Among Patients With Immune Thrombocytopenia
Patients who were older than 65 years, female, or hospitalized in the northeastern United States experienced increased incidence of intracranial hemorrhage.
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