Enasidenib Improves Some Outcomes, But Not Overall Survival, in Relapsed/Refractory Acute Myeloid Leukemia
Researchers sought to determine whether enasidenib would improve outcomes in patients with relapsed or refractory AML.
Diagnosis & Disease Information
AML Research From ASH 2022: Novel Combinations and Evidence That “Less is More”
AML research presented at ASH 2022 highlighted promising combination regimens and suggested that some patients may benefit from less intensive treatment.
G-CSF-Based Conditioning Regimen Recommended in MDS, Secondary AML Prior to HSCT
Researchers sought to determine whether patients with secondary AML or MDS would benefit from G-CSF-based conditioning prior to receiving HSCT.
Patient-Centered Communication Tool Feasible for Seniors With Acute Myeloid Leukemia
Patients, caregivers scored higher on AML knowledge and perceived greater efficacy in communicating with oncologists.
Prolonged Exportin-1 Inhibition Yields Antileukemic Activity in NPM1-Mutated Acute Myeloid Leukemia
Researchers sought to determine whether prolonged inhibition of exportin-1 would lead to antileukemic activity in an NPM1-mutated AML murine model.
Rezlidhia Now Available for Relapsed/Refractory AML With IDH1 Mutation
Rezlidhia is a small molecule inhibitor of mutated IDH1.
SLC22A3 Methylation Patterns Linked With Prognosis in Acute Myeloid Leukemia
Researchers sought to determine whether there was a relationship between methylation of the gene SLC22A3 and prognosis in different forms of AML.
Salvage Chemotherapy Before Allo-HSCT Does Not Improve Outcomes in Rel/Ref AML
Salvage chemotherapy before allogeneic transplant does not improve outcomes in relapsed/refractory acute myeloid leukemia, a phase 3 study suggests.
Less May Be More When Treating Newly Diagnosed AML
Neither a higher dose of daunorubicin nor a second induction cycle improved outcomes in fit patients with newly diagnosed acute myeloid leukemia.
Geriatric Assessment in Hematology Scale Predicts Treatment Tolerability in Older Patients With Hematological Malignancies
Researchers sought to assess the geriatric assessment in hematology scale in older patients diagnosed with hematological malignancies.
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