Until recently, the standard of treatment for many hematologic malignancies has largely consisted of combination chemotherapy and radiotherapy. As use of these conventional treatment strategies lessens, the role of targeted therapies continues to expand. However, despite the benefits of novel therapies, unique toxicity profiles warrant vigilant monitoring and personalized management by health care providers.

In a review article published in Expert Review of Hematology, Florian Simon, MD, of the department of internal medicine at the University of Cologne in Germany, and colleagues summarized current literature surrounding the use of novel agents for hematologic malignancies. They also reviewed relevant safety considerations and best practices in the management of therapy-related toxicities.

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