Radiomics: An Emerging Frontier in Cancer Diagnostics, Treatment Planning
This overview of radiomics explains its potential for improving diagnosis, predictions of tumor response and recurrence, and patient prognosis.
General Hematology
GENERAL HEMATOLOGY
FEATURE
LATEST NEWS
Combining Ruxolitinib With Donor Regulatory T Cells May Outperform Monotherapy in Chronic Graft Vs Host Disease
Researchers sought to determine whether combining ruxolitinib with donor regulatory T cells would improve outcomes of cGVHD.
Discordance in Symptomatic Adverse Event Reports by Clinicians, Children in Cancer Clinical Trials
An observational study sought to compare the perceptions of symptom burden in childhood cancer by children, clinicians, and caregivers.
HCVAD Induced High Response Rates in Blastic Plasmacytoid Dendritic Cell Neoplasm
Researchers sought to evaluate the outcomes of patients with BPDCN treated with HCVAD.
Patients With Polycythemia Vera Achieve Long-Term Treatment Goals With Ropeginterferon Alfa-2b
Researchers sought to determine whether long-term ropeginterferon alfa-2b would have benefits in patients with PV compared with hydroxyurea or the best available treatment.
Evusheld Appears Less Effective Against Omicron for Patients With Blood Cancer
A single 150 mg dose of Evusheld demonstrated neutralizing activity against wild-type SARS-CoV-2 but not the omicron variant.
Patient-Reported Outcomes and Overall Survival After Allogeneic Hematopoietic Stem Cell Transplantation
Researchers sought to find whether there was a relationship between patient-reported outcomes and overall survival after hematopoietic stem cell transplantation.
Momelotinib Bests Danazol in Symptomatic, Anemic Myelofibrosis
Momelotinib proved superior to danazol in patients with symptomatic, anemic myelofibrosis in a phase 3 study.
Varicella-Zoster Vaccination After Allogeneic Stem Cell Transplantation
Researchers sought to determine whether varicella-zoster virus vaccination with a recombinant vaccine would show results in patients who underwent HSCT.
Study: Nearly One-Third of Children With Hematologic Cancers Develop Cardiotoxicity
All patients with cardiotoxicity recovered within 2 months.
The Effect of Gender Bias in Surveys of Patients With Myeloproliferative Neoplasm
Gender balance in cancer surveys of patients with myeloproliferative neoplasms was found to have relatively little effect on survey outcomes.
Fylnetra, a Biosimilar to Neulasta, Gets FDA Approval
The approval was based on data demonstrating a high degree of similarity of Fylnetra to the reference product, with no clinically meaningful differences.
Risk of Cancer-Specific Death May Remain Elevated for 30 Years
Patients with certain cancers have an increased risk of cancer-specific mortality that persists for 30 to 35 years after diagnosis.
Data Reveal Disparities in Telemedicine Use Among Patients With Cancer
Researchers found that socioeconomic status, insurance, race, and rurality were all associated with telemedicine use.
Increasing Public Welfare Spending Can Improve Survival for Black Cancer Patients
A 10% increase in public welfare spending was associated with an 8.6% improvement in 5-year overall survival for Black patients with cancer.
Patients With Cancer at High Risk of Depression in Final 6 Months of Life
The final 6 months of life is presumed to be a high-risk period for depression and anxiety in patients with cancer. However, few studies have examined whether depression and anxiety do occur in the last year of life and to what extent.
Hospitalizations and Costs With Steroid Use for Graft-Versus-Host Disease
A study sought to determine the impact of infection, gastrointestinal, bone/muscle, and metabolic/endocrine complications in patients receiving steroids for GVHD on HCRU and costs.
Leukocyte-Endothelial Interactions May Be Marker for Outcomes After HCT
Researchers sought to determine whether leukocyte A&R would be linked with cancer relapse and survival after hematopoietic cell transplant.
ROCK1/2 May Be Novel Therapeutic Target in Myeloproliferative Neoplasms
Researchers sought to determine whether inhibiting ROCK1/2 when using interferon therapy would be effective in patients with MPNs.
Analysis of Hepatitis C Virus Genotypes Among US Blood Donors From 2003 to 2018
Researchers assessed the characteristics and distribution of hepatitis C virus (HCV) genotypes among individuals with confirmed HCV infection who donated blood during a 16-year period.
LMNB1 Gene Deletion Associated With Change in Nuclear Structure in Myeloid Neoplasms
Researchers sought to determine whether there is a link in loss of LMNB1 expression with changes in myeloid neoplasms.
Blood TMB May Predict Response to Atezolizumab in Non-Small Cell Lung Cancer
Having a high blood tumor mutational burden was associated with a significant improvement in response and a trend toward improvement in survival outcomes.
Vaccination-Based Method to Promote Secretion of GM-CSF After Allogeneic HSCT Does Not Improve Survival
Researchers sought to determine whether a vaccination-based method to promote secretion of GM-CSF after alloHSCT would improve survival outcomes.
Most Blood Cancer Drug Trials Are Not Randomized, Use Surrogate Endpoints
Of more than 2500 trials analyzed, 21% were randomized.
Validation of Nursing Skills Improves Central Line Infection Rates on HSCT Unit
A project to reverse an increase in CLABSIs on an HSCT inpatient unit and its ongoing impact were described at the Annual ONS Congress.
Engaging Patients to Improve Genetic Risk Assessment and Testing
Preliminary results of a study comparing outreach methods for engaging patients in genetic risk assessment and testing are presented.
Cancer Researchers Aren’t Reporting Quality of Life Outcomes Accurately
Quality of life outcomes were reported favorably for trials that showed no improvement in quality of life.
Mesenchymal Stromal Cells Improve Response to Second-Line aGVHD Therapy
Researchers sought to determine whether adding MSC to basiliximab and a calcineurin inhibitor would improve outcomes in patients with aGVHD after HSCT.
Antibiotics Within the Same Class May Not Be Ideal in Combination Therapy for Bloodstream Infections
Researchers assessed the efficacy and interaction between the 4 most common antibiotic combinations for Escherichia coli bloodstream infections.
NCCN: Most Cancer Patients Should Receive 5 Doses of an mRNA COVID-19 Vaccine
Most cancer patients should receive 3 primary doses of an mRNA COVID-19 vaccine and 2 booster doses, according to NCCN.
Books, Movies, and Journaling Aid Coping During, After Cancer Treatment
An exploration of complementary therapies that help patients cope during and after treatment for cancer.
Potential of Cannabis, Cannabinoid Products in Managing Cancer Symptom Burden
Researchers conducted a literature search for evidence of the effects of medical marijuana products on symptom burden in patients with cancer.
Health-Promoting Behaviors: A Measure of Caregiver Burden in the Cancer Setting
Researchers sought to classify health-promoting behavior levels among family caregivers of patients with cancer and to identify risk factors for low levels.
Disparity in Access to CAR-T Therapy Associated With Lower Income Neighborhoods
Researchers sought to determine the reasons for a disparity in patients who receive CAR-T therapy.
Lymphopenia Tied to Risk of Infection After Radiotherapy
Measuring lymphocytes during or after radiotherapy could provide useful information about infection risk, according to researchers.
Outcomes of Pediatric Patients With Steroid-Refractory Acute Graft Vs Host Disease
The aim of this study was to evaluate the outcomes of pediatric patients who develop SR-aGVHD during a 10-year time period.
Addressing the Financial Burden of Young Adult Cancer Survivors: Is Medical Crowdfunding a Solution?
Researchers investigated how young adult cancer survivors felt about using medical crowdfunding to help cover their healthcare and basic living costs.
Idasanutlin Reported as Clinically Active, But Has Poor Tolerability in Patients With Polycythemia Vera
Researchers sought to evaluate the activity of idasanutlin in patients with HU-resistant/-intolerant polycythemia vera.
Biomarkers May Help Guide Treatment in Cancer Patients With COVID-19
Three biomarkers were associated with prognosis after COVID-19 treatment.
Pandemic Exacerbates Disparities in Outcomes for Pediatric Cancer Patients
Pediatric cancer patients in low- and middle-income countries had a nearly 16-fold higher risk of all-cause mortality within 30 days of presentation, when compared with their counterparts in high-income countries.
Genetically Modified IECs Do Not Increase Risk for Subsequent Malignancy
Researchers conducted a retrospective study comparing the incidence of second malignancy in cancer patients treated with genetically modified immune effector cells with those who received unmodified cells.
Chemo at Home: High Rate of Satisfaction, Low Rate of Discontinuation
Most patients completed at-home chemotherapy infusions as planned, and no one stopped treatment because of adverse drug reactions.
Cancer Screening: A Review of Guidelines from ACS, USPSTF
A presentation at the ONA Summit reviewed the cancer screening guidelines from the ACS and USPSTF.
Monoclonal Antibodies Lower Risk of COVID-19 Hospitalization in Cancer Patients
There was no significant difference in post-infusion hospitalizations between patients with and without a history of cancer.
Sexual and Emotional Health Impacts of Allogeneic Hematopoietic Stem Cell Transplantation
Researchers sought to determine the impacts on sexual and emotional health following allogeneic hematopoietic stem cell transplantation.
Long-Term Risks Examined for Survivors of Adolescent, Young Adult Hematologic Cancers
Risks for secondary malignant neoplasms, hospitalizations, overall mortality up, with differences for leukemia and lymphoma survivors
Nearly 1 in 10 Cancer Patients May Not Receive Guideline-Concordant Care
The highest rate of non-concordant care was seen in patients with cervical cancer.
Phthalates in Medications May Increase Risk of Childhood Cancers
Children prescribed a medication containing a phthalate had a 19% higher risk of developing any childhood cancer.
Half of Cancer Patients Lost Neutralizing Antibodies 6 Months After COVID-19 Vaccination
Roughly half of patients with hematologic cancers or solid tumors lost neutralizing antibody responses to SARS-CoV-2 variants of concern at 6 months after vaccination.
Supplementation Improves QOL in Iron Deficiency With Solid Tumors
Researchers sought to determine whether iron supplementation would improve quality of life and functional capacity of patients with cancer who develop iron deficiency.
Patients’, Caregivers’ Perception of Care Better With Palliative Care Pathway
An interviews conducted with patients and caregivers demonstrated the effects of an early palliative care pathway for advanced colorectal cancer.
- Loading...
Loading...
Want to read more?
Please login or register first to view this content.
Next post in General Hematology
Loading... 
Loading...