Caring for the Caregivers of Patients With Hematologic Malignancies Undergoing HSCT
Researchers sought to address the needs of caregivers of patients with hematologic malignancies undergoing HSCT.
General Hematology
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Ruxolitinib Shows Promise in Treatment-Resistant PV
Researchers sought to determine whether ruxolitinib would improve clinical outcomes in patients with treatment-resistant PV.
Aromatherapy Improved Management of Chemotherapy-Induced Nausea and Vomiting
Randomized trial compared effects of ginger oil, peppermint oil, and canola oil on CINV in patients receiving chemotherapy prior to bone marrow transplantation.
Machine Learning Algorithm Shows Promise in Determining BMF Etiology
Researchers sought to determine whether a novel machine learning algorithm could help determine whether a patient has inherited or immune/acquired BMF.
Changes to Primary Endpoints of Cancer Trials Are Not Being Disclosed in Manuscripts
Changes to primary endpoints of phase 3 cancer trials may be common and underreported, a study suggests.
New Risk Score Assists in Predicting Myeloid Neoplasms in Individuals With Clonal Hematopoiesis
Researchers sought to develop a clonal hematopoiesis risk score for patients with CHIP and CCUS to determine whether it can predict risk of developing myeloid neoplasm.
Few Cancer Drugs Are Approved Within 10 Years of Entering Trials
The probability that a cancer drug would receive FDA approval within 10 years of entering trials was 10.4%, researchers found.
Effect of Prognostic Awareness on Patient Preferences and Psychological Outcomes
The prospective, multicenter NEOetic study explored relationships between patient prognostic awareness and decisions regarding treatment.
About 20% of Oncologists Studied Left Patient-Facing Positions Between 2015 and 2022
In a study of 16,870 oncologists practicing in the United States, 21% left patient-facing roles between 2015 and 2022.
MIS-C Increases Risk of Hospitalization, Death in Cancer Patients With COVID-19
Pediatric cancer patients who develop MIS-C after COVID-19 have a worse clinical course than patients without MIS-C, a study suggests.
Risks Associated With COVID-19 Pandemic Caused Anxiety Among Cancer Patients
Cancer patients reported concerns about the risks that COVID-19 poses to themselves and their family, how delayed care might affect their outcomes, and the social and economic impacts of the pandemic.
Lack of Diversity on Editorial Boards for Hematology/Oncology Journals
A majority of editorial board members from high-impact hematology/oncology journals are non-Hispanic White men, according to a recent study.
Exploring Patients’ Perceptions of Quality of Cancer Care in the Outpatient Setting
Interview study explored how patients perceive the concept quality of cancer care in the outpatient setting.
Cancer Patients Report Better Experiences With Telemedicine Than With In-Person Care
Cancer patients who use telemedicine report better experiences than cancer patients treated in person, according to a new study.
New Documentation Tool Improves Telephone Triage in Oncology Pain Management
A new pain assessment documentation tool is helping nurses in an ambulatory clinic better manage telephone triage in oncology care.
Educational Program Developed to Improve Communication About Clinical Trials
Researchers sought to develop an educational program to improve communication between patients and caregivers and doctors about care and clinical trials.
New Scale Quantifies Workload, Increases Productivity of Oncology Nurse Navigators
Study results show a new productivity scale measures the workloads of oncology nurse navigators and assists in increasing their productivity.
Disrupting the Status Quo: ACCESS Initiative Takes Aim at Inequities in HCT, Cellular Therapy
NMDP/Be The Match and the ASTCT seek to address inequities in HCT and cellular therapy.
FDA Updates Recommendations for Assessing Blood Donor Eligibility
The time-based deferrals for men who have sex with men (MSM) and women who have sex with MSM have been eliminated.
Researchers Developed Algorithm to Test for Clostridioides difficile Infection After HSCT
Researchers sought to determine a method of testing hematopoietic stem cell transplantation recipients for Clostridioides difficile as a cause of diarrhea.
How Different Components of Palliative Care Services Affect End-of-Life Care
During end-of-life care, cancer patients who utilized spiritual, psychology, and social work services received different oncologic treatment.
High Frequencies of Myeloid-Derived Suppressor Cells Seen in Patients With Myeloproliferative Neoplasms
Researchers sought to determine the frequency of myeloid-derived suppressor cells in bone marrow of patients with MPN.
Biosimilar Use on the Rise in Oncology Practices
Researchers looked at the use of 6 biosimilars across 38 oncology practices and found that biosimilar use increased from 2019 to 2021.
Associations Between Cancer and COVID-19 Death “More Substantial” in Women
The risk of in-hospital death from COVID-19 for patients with cancer differs by sex and cancer type, according to a new study.
Cancer Death Rates Higher in NHPI Patients Than in Asian Patients
A new study has revealed “stark” differences in cancer death rates between Asian patients and NHPI patients in the US, according to researchers.
Fall Prevention Algorithm Reduces Falls Among Hematology/Oncology Patients
A quality improvement project sought to reduce falls and falls with injury among inpatient hematology/oncology patients.
Cryopreserved Allogeneic Hematopoietic Cell Grafts Did Not Impact OS During COVID-19 Pandemic
Researchers sought to determine whether using cryopreserved hematopoietic stem cell grafts during the COVID-19 pandemic impacted OS compared with fresh grafts.
Advanced Practice Nurse, Pharmacist Collaboration Leads to Improved Outcomes on HSCT Unit
A project designed to improve the interaction within a multidisciplinary team on a HSCT unit was presented at the 48th Annual ONS Congress.
Intervention Training Oncology Nurses Improves Management of CAR-T Therapy
A team of HSCT nurses developed a training program for oncology nurses to improve the care of patients with hematologic cancer outside the transplantation unit.
Menstrual Disturbances Not Being Tracked, Treated in Cancer Patients
New research suggests that some cancer patients do not have their menstrual history documented and do not receive treatment for menstrual disturbances.
FDA Approves Omisirge, an Allogeneic Cell Therapy for Patients With Blood Cancers
Omisirge is a nicotinamide modified allogeneic hematopoietic progenitor cell therapy derived from cord blood used as an allogeneic stem cell donor source.
Dabrafenib-Trametinib Combo Proves Active in Rare BRAF-Mutated Cancers
Combination dabrafenib and trametinib has demonstrated activity against multiple rare cancers harboring the BRAF V600E mutation.
Pediatric Cancer Survivors Have 4-Fold Higher Risk of Death 40 Years After Diagnosis
From 15 to 40 years after diagnosis, pediatric cancer survivors have a roughly 4-fold higher risk of death than the general population, a study suggests.
Cancer Survivors More Likely to Use Cannabis for Medical Purposes
Compared to the general public, cancer survivors are more likely to use cannabis for medical purposes but less likely to use cannabis in general, a study suggests.
Pruritus May Mark Severe Symptomology in Myeloproliferative Neoplasms
Researchers assessed clinical incidence of pruritus in patients with myeloproliferative neoplasms.
Similar Vaccine Responses After Pneumococcal Vaccination Following Allogeneic Hematopoietic Stem Cell Transplant
Researchers sought to determine whether responses to the pneumococcal vaccine would vary between patients after HCT at 3 or 6 months.
Trust in Clinicians Linked to Likelihood of Clinical Trial Enrollment by Black Patients
Researchers sought to identify the factors that resulted in a high proportion of African American patients with multiple myeloma participating in the Winship clinical trials.
Perceived and Received Social Support for Child and Adolescent Cancer Survivors
Friends and family, especially parents, are the greatest sources of social support for childhood and adolescent cancer survivors.
Outcomes of Chemotherapy-Related Febrile Neutropenia Vary by Region
Research has revealed regional disparities in outcomes for patients who are hospitalized with chemotherapy-related febrile neutropenia in the United States.
Preventing and Treating COVID-19 in Cancer Patients: Challenges in the Omicron Era
Methods to prevent and treat COVID-19 in cancer patients have had to evolve alongside the SARS-CoV-2 virus.
The Burden and Current Management of Cisplatin-Induced Ototoxicity
A recent review highlights the burden of cisplatin-induced ototoxicity and the current state of monitoring and managing this condition.
NGS Reveals Actionable Mutations, Leads to Diagnosis in Cancer of Unknown Primary
NGS can reveal targetable mutations and aid diagnosis for patients with cancer of unknown primary, a study suggests.
US Medical Oncologists Are Prescribing Fewer Opioids
Medical oncologists in the United States have been writing fewer prescriptions for opioids since 2017, a new study suggests.
TP53 Mutations Confer High Risk in Patients With Myelofibrosis Undergoing HSCT
Researchers sought to determine the impact of TP53 mutations on HSCT outcomes in patients with myelofibrosis.
Ongoing Disruptions in Cancer Care Due to COVID-19
Patients with cancer continued to experience COVID-19-related disruptions to their care in 2022, results of a survey suggest.
Distance From Fertility Center Affects Use of Fertility Preservation by Male Patients With Cancer
A retrospective cohort study sought to determine the impact distance from the clinic has on the likelihood of male patients with cancer to participate in fertility preservation.
Pelabresib With Ruxolitinib Shows Improvements in Patients With JAK Inhibitor-Naïve Myelofibrosis
Researchers sought to determine whether combination therapy with pelabresib and ruxolitinib would lead to improvements in spleen reduction volume in myelofibrosis.
FDA Issues Complete Response Letter for Ruxolitinib Extended-Release Tablets
The letter states that the application cannot be approved in its present form.
Secreted Mutant Calreticulins Act as Cytokines in Myeloproliferative Neoplasms
Researchers sought to determine the role of mutant calreticulin in the proliferation of hematopoietic cells in patients with MPNs.
Joenja Approved for Activated Phosphoinositide 3-Kinase Delta Syndrome
Joenja is supplied as 70mg tablets in 60-count bottles; it is expected to be available in early April 2023.
Hydroxyurea Does Not Appear to Increase Second Malignancy Risk in Myeloproliferative Neoplasms
Researchers sought to determine whether treatment with hydroxyurea for patients with MPNs would lead to a higher risk of secondary malignancies.
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