Some US medical centers have canceled treatments and all centers have altered their policies and procedures out of precaution related to the COVID-19 pandemic.
Although most notably associated with erythrocytosis, hematologic manifestations of polycythemia vera may also include leukocytosis and thrombocytosis.
Alternating patient position during PEEP was found to improve lung recruitability of patients with ARDS related to COVID-19 infection.
Whether aggressively pursuing diagnosis in some cases retains the margin between benefit and consequence is, unfortunately, often unclear.
Convalescent plasma, which is collected from patients who have recovered from COVID-19, contains antibodies to SARS-CoV-2, the virus that causes the disease.
After identifying bottlenecks at a VA hospital infusion clinic in Alabama, better communications and establishing a fast-track clinic for some patients led to a 23% reduction in infusion clinic wait times.
During a routine physical examination, a clinician suspects May-Hegglin anomaly because of the patient’s low platelet count and hearing loss.
Researchers sought to determine whether second cancers associated with MPNs affect a patient’s prognosis, and whether cytoreductive or antiplatelet therapies affect outcomes.
For this retrospective analysis, researchers reviewed data from 7 patients treated with nivolumab for relapsed/refractory EBV-HLH to determine its effectiveness in this setting.
The authors of this article emphasized the importance of actively involving a diverse group of interdisciplinary team members in the psychosocial care of these patients.
Researchers conducted a meta-analysis of 7 studies involving NHL and 3 focused on MM to determine the role of occupational exposure to glyphosate in terms of risk.
One finding from this study was that VTE was more likely to occur at atypical sites in patients with myelofibrosis compared to those without the disease.
Older adults are often underrepresented in trials either because of comorbidities that cause them to be excluded, or through unconscious bias on the part of study teams.
How should clinicians combat coronavirus disease (COVID-19) in their practice settings?
Preliminary results of a study on burnout among oncology clinicians, researchers report that a team-oriented program can be effective.
Although some patients with cancer are at higher risk of developing severe disease should they become infected, these experts suggest the precautions being given to the general population are sufficient — at least for now.
A 3-cycle Plan-Do-Study-Act intervention resulted in increased nurse and physician education on mucositis and a nurse-driven protocol that reduced MBI-LCBIs by 25%.
In the extension study, 53% of patients receiving ropeginterferon alfa-2b met the primary end points, compared with 38% of patients receiving hydroxyurea.
Researchers provided an overview of toxicities associated with the use of novel agents to treat hematologic malignancies, as well as potential management strategies.
Lower microbiota diversity both before and after allogeneic hematopoietic cell transplantation was associated with poorer survival.
Researchers examined pregnancy outcomes in 102 patients with essential thrombocythemia.
By week 24 of the study, a reduction in palpable spleen length of at least 50% was reported in more than half of patients who underwent splenomegaly.
Higher proportions of patients receiving olanzapine reported only mild or no nausea compared with patients receiving placebo.
Treatment regimens including immunomodulatory agents or proteasome inhibitors could lead to development of peripheral neuropathy.
Symptom burden may be higher in patients with persistent cGVHD compared with patients with recently diagnosed cGVHD.
Researchers assessed the incidence of various hematologic disorders in patients with bulimia nervosa and anorexia nervosa.
Of clonal mutations found in donors, 84.2% were predicted to be molecularly pathogenic and 100% engrafted in recipients.
Several factors need to be considered when choosing optimal therapy for older patients with hematologic malignancies, particularly when it comes to managing toxicity.
For children with Kawasaki disease (KD), the use of low-dose aspirin, rather than high-dose aspirin, may not increase risk for recrudescent fever when given in combination with intravenous immunoglobulin (IVIG), according to study results published in JAMA Network Open. The study was a retrospective cohort analysis that included 260 patients with KD who were treated…
Researchers assessed how the reasons that led to discontinuation of ruxolitinib influenced survival in patients with myelofibrosis.
The study’s primary endpoint was efficacy, determined by complete remission, peripheral blood cell count remission, quality of life, and JAK2 V617F allele burden.
Caroline O. Pardo, Ph.D., General Manager for Haymarket Medical Education, is pleased to announce that HME, based in Paramus, NJ, has been accredited as a provider of interprofessional continuing education by the Accreditation Council for Continuing Medical Education, the Accreditation Council for Pharmacy Education, and the American Nursing Credentialing Center.
Patients who received aspirin exhibited levels of PAC-1 binding to platelets similar to those seen in healthy control individuals.
Researchers identified 3 risk factors that were associated with the development of moderate to severe chronic graft-versus-host disease.
Patient-hematologist discordance in perceived chance of cure appears to improve after a hematology consultation.
Infection occurred in 60% of patients with systemic light-chain amyloidosis who were treated with intravenous daratumumab.
Researchers implemented a multidisciplinary team clinic approach to assess candidacy of older adults for hematopoietic cell transplantation.
Researchers assessed clinical outcomes and characteristics of acute and chronic graft-versus-host disease after prophylaxis with alemtuzumab.
Researchers reviewed currently available point-of-care technology and provided recommendations for standardizing use of this technology.
Treatment with aspirin or interferon was associated with increased odds of live birth among pregnant patients with myeloproliferative neoplasms.
Although some red blood cell-related parameters used in the diagnosis of PV may be misleading in the setting of iron-deficiency, RBC count may be an effective biomarker for PV when combined with ESR.
This nonrandomized study enrolled more than 100 patients with essential thrombocythemia or polycythemia vera resistant to or intolerant of hydroxyurea to determine if interferon alfa-2a is effective in these patients.
An investigational gene therapy has been granted Orphan Drug designation from the Food and Drug Administration for the treatment of Gaucher disease.
Patients with viral respiratory infections exhibited poorer outcomes following transplantation compared with patients without infection.
Poverty was associated with lower rates of allogeneic hematopoietic stem cell transplantation, even after adjusting for race and rural residency.
Patients with blood cancers were more likely to enroll in hospice earlier if they included a hematologic oncologist in their first discussion about their goals of care.
Patients demonstrated similar rates of live births and thrombotic complications, but the most common complication was different for each group.
Researchers found a 1.12 ratio of blood product need to supply, and 61% of countries included in the analysis had an insufficient supply of blood products.
Red blood cell distribution width above the calculated cutoff of 13.8% was significantly associated with poorer overall survival.
Older patients with AF who have contraindications to oral anticoagulation because of high bleeding risk have increased mortality compared with untreated patients who have no contraindications.
In a retrospective service evaluation of patients with MPNs, researchers found that low-dose methotrexate eased symptom burden of comorbidities not related to the patient’s MPN.