AYA-Specific Programs Bridge Gap Between Pediatric and Adult Oncologic Services
This review describes specialized programs for adolescent and young adults with cancer and the process undertaken by a US facility to develop its program.
General Hematology
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Mindfulness Program Reduces Burnout, Compassion Fatigue in Nurses
A study sought to determine if mindfulness-based stress reduction would ease compassion fatigue and burnout among the facility’s pediatric oncology nurses.
Study Reveals Pregnancy-Related Discrimination in Oncology
Nearly a third of female oncologists surveyed said they experienced some form of discrimination during pregnancy.
“Race Against Time” to Find Cancers Missed During COVID-19 Pandemic
The COVID-19 pandemic has hindered the early diagnosis and treatment of cancer, and this may have set back cancer outcomes by almost a decade in Europe, a new report suggests.
Atezolizumab Plus R-CHOP Deemed Unworthy of Additional Study in Diffuse Large B-Cell Lymphoma
Results of a phase 1/2 trial suggest the combination of atezolizumab and R-CHOP does not warrant further study in DLBCL, according to researchers.
Lenalidomide May Select for TP53-Mutated Clones, Increasing Risk of Therapy-Related MNs
Researchers sought to determine the role of lenalidomide in the pathogenesis of therapy-related myeloid neoplasms.
Assisting Survivors Through Grief After the Loss of a Co-Parent to Cancer
A qualitative study sought to investigate the challenges faced by a surviving parent of dependent children after the cancer-related death of a co-parent.
Cancer Therapy Deemed Safe for COVID-19 Patients Without Immunosuppression
In the absence of immunosuppression, systemic cancer therapies do not increase the risk of severe COVID-19 or cytokine storm, a study suggests.
High-Dose Dexamethasone Not Recommended for Dyspnea With Cancer
A randomized clinical trial sought to determine if high-dose dexamethasone would be an effective palliative treatment of dyspnea in patients with cancer.
How Stigma Influences Patients’ Perspectives on Opioids for Cancer-Related Pain
Interviews with patients with advanced cancer and their support providers identified concerns they have regarding use of opioids for pain management.
Attitudes Toward Quality of Life, Length of Life Change Throughout Advanced Cancer
A secondary analysis of the CHOICE trial explored patients’ attitudes toward striving for quality of life and/or length of life throughout their cancer care.
Inpatient Oncology Service Improved Readmission and Discharge to Hospice
Researchers sought to determine whether implementing inpatient oncologist-led teams could reduce readmission rates and improved discharge to hospice.
CDC Releases Updated Guidance on Prescribing Opioid Pain Medication
The 2022 CDC Clinical Practice Guideline is intended to help clinicians weigh the benefits and risks of opioids and alternative pain treatments for outpatients.
Fewer Serious Adverse Events Reported in Cancer Trials During COVID-19 Pandemic
Serious adverse events were reported less frequently among patients enrolled in cancer trials during the first 2 years of the COVID-19 pandemic than among patients enrolled prior to the pandemic.
Demographic Disparities Linked to Collected Cancer Family History Information
A retrospective review of electronic health records in 2 large healthcare systems identified patients whose incomplete health information may contribute to disparities in cancer care.
Improved Outcomes Seen With Combined Cyclophosphamide and Antithymocyte Globulin in PBSCT
Researchers sought to determine if the combination of PTC-gamma and low-dose antithymocyte globulin could improve efficacy in patients who underwent haplo-PBSCT.
Proton FLASH Radiotherapy Deemed Feasible, Comparable to Conventional Dose Rate Radiotherapy
Proton FLASH radiotherapy is feasible, safe, and provides pain relief for cancer patients with bone metastases, according to a first-in-human trial.
Meta-Analysis Clarifies Risk of Cutaneous AEs Associated With PI3K Inhibitors
The incidence of cutaneous adverse events in cancer patients receiving PI3K inhibitors may be as high as 29%, a meta-analysis suggests.
Impact of Sexual Trauma and Need for Trauma-Informed Oncology Care
This review article discusses how cancer care may cause survivors of sexual trauma to re-experience their trauma and offers tips on how to mitigate this potential.
Eligibility Not Responsible for Under Representations in Cancer Clinical Trials
Researchers sought to determine which patient demographics and clinical characteristics affected participation in cancer clinical trials.
Cost and Coordination of Care Head List of Concerns With Combination IV/Oral Therapy
Results of an ACCC study revealed advanced practitioners’ greatest challenges when treating cancer patients with combination IV/oral therapies.
COVID-19 Vaccination Should Not Interrupt ICI Therapy, Researchers Say
COVID-19 vaccination is safe for cancer patients receiving immune checkpoint inhibitors and should not interrupt therapy, according to researchers.
Rolvedon Now Available for Chemotherapy-Induced Neutropenia
Rolvedon is a long-acting granulocyte colony-stimulating factor.
Simulation With Task Trainers Improved BMT Procedure Skills, Knowledge
A poster presentation at JADPRO Live 2022 described the benefits of using simulation training in combination with didactic educational sessions to improve knowledge and confidence for bone marrow transplant APPs.
Still Unclear Whether Intermittent Fasting Can Improve Cancer Outcomes
Intermittent fasting appears safe as an adjunct to chemotherapy, but it is unclear whether this diet can improve cancer outcomes.
Diverticular Disease Associated With Increased Risk of Multiple Cancers
Patients with diverticular disease had an increased risk of lung, prostate, breast, hematologic, colorectal, gastric, liver, and pancreatic cancers.
Hematopoietic Stem Cell Transplantation Shows Positive Efficacy for Inborn Errors of Immunity
Researchers sought to identify outcomes for adolescents and adults with inborn errors of immunity treated with HSCT.
SAFER Ukraine: A Global Effort to Evacuate Children With Hematologic Cancers From Ukraine
The SAFER program is helping Ukrainian children with cancers and other blood disorders to continue their therapy in Ukraine at centers in Europe and North America.
Better Clinician Support Needed to Improve Exercise Counseling for Cancer Survivors
Results of an online survey designed to measure gaps between healthcare practitioners knowledge and practice regarding exercise for cancer survivors are presented.
Pain in Cancer Requires Holistic Approach, Multidisciplinary Care Team
Researchers conducted a literature search to better understand the multidimensionality of pain, its evaluation, and management.
Guideline Released on Integrative Medicine for Pain Management in Oncology
The Society for Integrative Oncology and American Society of Clinical Oncology issued a joint guideline on use of integrative medicine for pain management in oncology.
Oncology Care Model Did Not Decrease Use of Expensive Novel Therapies
Medicare’s Oncology Care Model (OCM) did not deter oncologists from prescribing more expensive novel cancer therapies.
Hypoxic Storage of Red Blood Cells Mitigates Storage Lesion
Researchers sought to determine whether storing RBCs in a hypoxic environment would improve functional outcomes of RBCs in long-term storage.
Endoscopic Procedures Improve Gastroesophageal Variceal Rebleeding in MPN
Researchers sought to determine the efficacy of endoscopic management of recurrent GVB in patients with MPN.
UBA1 Mutation Subtypes Linked With Survival and Clinical Outcomes in VEXAS Syndrome
Researchers sought to determine whether certain subtypes of UBA1 mutations impacted survival outcomes in patients with VEXAS syndrome.
Medical Aid in Dying: What Oncology Providers Need to Know
Data suggest that most patients who use medical aid in dying (MAID) have cancer, but some oncology providers do not feel well informed about MAID.
Oncodental Team Established to Prevent Life-Threatening Infections in Children With Cancer
Researchers sought to determine whether creating a pediatric oncodental team would help prevent oral-systemic infection in high-risk children with cancer.
Bevacizumab Biosimilar Alymsys Now Available
Alymsys is a vascular endothelial growth factor inhibitor.
Open-Label Placebo Effective for Cancer-Related Fatigue With Advanced Cancer
Researchers sought to measure outcomes for cancer-related fatigue in patients with advanced cancer treated with open-label placebo, compared with a waitlist control group.
Itacitinib Monotherapy Appears Safe, Effective for Acute, Low-Risk Graft Vs Host Disease
Researchers sought to determine whether itacitinib would be an effective therapy for patients with low-risk, acute GVHD.
COVID-19 Vaccines, Treatments Appear to Reduce Risk of Death in Patients With Hematologic Malignancies
The 30-day mortality rate was higher before the availability of vaccines, and the use of monoclonal antibodies alone or in combination with antivirals was associated with a lower risk of death.
QTc Formula Affects Heart Rhythm Assessment, Chemotherapy Dose
Researchers discovered a discrepancy between QT interval formulae used to assess heart rhythm and determine chemotherapy doses in a patient with leukemia.
Acupuncture and Moxibustion for Insomnia Relief in Cancer Patients
Acupuncture and moxibustion, which are sometimes used together, have shown promise in reducing insomnia in patients with cancer.
Oral Care Protocol Eased Severe Oral Mucositis Due to HSCT Conditioning Regimen
Researchers investigated whether bovine colostrum- and Aloe vera-based products would ease severe oral mucositis in patients undergoing hematopoietic stem cell transplantation.
Rising Costs of Oral Anticancer Drugs Burden Medicare Recipients; New Law May Provide Some Relief
New data highlight the high cost of targeted oral anticancer medicines for patients with Medicare Part D coverage.
AYA Cancer Diagnosis Does Not Confer Greater Risk for Stillbirth
Being diagnosed with cancer as an adolescent or young adult does not confer an additional risk for stillbirth, a new study suggests.
Symptom Patterns Change Over Time, Even Vary Among Patients With Similar Experiences
A longitudinal analysis sought to determine how symptom patterns may be used to plan symptom management for patients with cancer.
Changing Abortion Laws Cast Uncertainty on Future of Fertility Preservation
Changes to abortion laws in the US could have unintended consequences for cancer patients and others seeking fertility preservation.
Outpatient Opioid Use Influences Pain Outcomes in the ED for Patients With Cancer
Researchers sought to identify the characteristics likely to precipitate ED visits for pain among patients with cancer.
Increased Risk of MGUS Among World Trade Center Rescue and Recovery Workers
Researchers sought to determine if the risk of developing MGUS was present in a more heterogeneous population of World Trade Center rescue and recovery workers.
Rolvedon Approved for Chemotherapy-Induced Neutropenia
Rolvedon is a novel, long-acting granulocyte colony-stimulating factor comprised of 2 protein components, an analogue of G-CSF and an Fc antibody fragment.
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