The neurodynamics nerve flossing technique (NFT) had a positive effect in the treatment of femoral neuropathy in children with hemophilia, according to the results of a recent study published in the Journal of Musculoskeletal and Neuronal Interactions.

The investigators studied the impact of neurodynamics NFT on femoral neuropathy in patients with hemophilia. Patients were randomly assigned (1:1) to 2 treatment groups: an NFT group, which received neurodynamics NFT of the femoral nerve, and a control group, which received conventional therapy. Patients received their respective therapy at 3 sessions per week for 12 weeks. Femoral nerve motor conduction velocity (MCV) and pain sensation level using the visual analogue scale were evaluated at baseline and after 12 weeks of treatment.

A total of 30 boys with moderate to severe hemophilia A or B were included in the study. Their ages ranged from 12 to 15 years. Patient characteristics between the treatment groups (n=15 each) were well balanced.

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Following treatment, patients in both groups showed improvement in femoral nerve MCV (pre- to post-treatment mean difference: neurodynamics NFT group, -13.760; P =.0001; control group, -11.11; P =.0001) and reduction of pain level (pre- to post-treatment mean difference: neurodynamics NFT group, 4.6; P =.0001; control group, 2.87; P =.0001). For the neurodynamics NFT and control group, these results translated to percent improvements relative to baseline of 42% and 34% for the femoral nerve MCV and 65% and 40% for pain level, respectively.

Patients in the neurodynamics NFT group showed a significant increase in femoral nerve MCV compared with that of the control group (post-treatment mean difference, -2.43; P =.0001) and reduction of pain level (post-treatment mean difference, 1.866; P =.0001).

The primary limitation of this study was the inability to investigate the long-term effect of NFT on quality of life, leading the authors suggest that future studies on this are needed.

“The Neurodynamics Nerve Flossing should be considered as an effective physical therapy intervention in hemophilic patients with femoral neuropathy, as it showed a significant improvement in motor function outcomes and a significant reduction in pain scores,” the authors concluded in their report.


Hamed SA, Zoheiry IM, Waked NM, Saad El-Din Mahmoud L. Effect of neurodynamics nerve flossing on femoral neuropathy in haemophilic patients: a randomized controlled study. J Musculoskelet Neuronal Interact. 2021;21(3):379-386.