Researchers conducted 2 sets of literature reviews to determine whether the professional society recommendations for >50% factor levels during labor in patients with hemophilia was accurate.
Hemophilia is a bleeding disorder caused by a genetic mutation that is often inherited. Patients who are at risk and parents or caregivers of children at risk of hemophilia may need additional education about what causes hemophilia and how it is diagnosed and treated.
Researchers sought to determine whether recombinant factor VIII-Fc fusion protein would have greater efficacy as prophylaxis therapy over emicizumab in patients with hemophilia A.
Findings from a retrospective chart review showed a need to carefully monitor inflammatory biomarkers and anticoagulant dosage in patients with severe COVID-19.
Researchers performed an analysis to determine whether recombinant VWF given with surgery would be safe and effective in preventing bleeding in patients with VWD.
Researchers sought to determine whether physiotherapy and exercise would be an effective therapy for increasing functionality, joint health, and quality of life in patients with hemophilic arthropathy of the elbow.
DECKNonpharmacologic treatment with cognitive-behavioral therapy combined with physiotherapy may be an effective pain management strategy for patients with severe hemophilia.
Findings from a retrospective chart review showed a need to carefully monitor inflammatory biomarkers and anticoagulant dosage in patients with severe COVID-19.
Results of a rodent model show that fibrin-specific core-shell nanogels with a tissue-type plasminogen activator warrants more study as a treatment for patients with DIC.
Whether inherited or acquired, bleeding disorders can cause significant pain, inconvenience, and stress in a person’s life. When patients think they or a loved one may have a bleeding disorder, what should they know?
A group of US-based hemophilia experts summarized unmet needs in mild to moderate hemophilia and provided suggestions for healthcare professionals to optimally manage their patients with this challenging condition.
Pediatric patients with hemophilia may have impairments in postural balance, which could be an early sign of musculoskeletal disorders, and its assessment should be included in evaluations.
These guidelines from ASH, ISTH, NHF, and WFH are intended to support patients, clinicians, and healthcare professionals in their decisions affecting the management of VWD.
This study aimed to investigate the effects of manual therapy combined with home exercises for young adult patients with hemophilic arthropathy of the lower limb joints.
A team of investigators evaluated clinical characteristics, hemostasis management, and clinical outcomes of bleeding events in women and girls with hemophilia.
A population-based analysis suggested that plasma levels of von Willebrand factor may be a potential biomarker for the future risk of incident venous thromboembolism.
Among pediatric patients with congenital fibrinogen deficiency, the administration of human fibrinogen concentrate may be efficacious for on-demand treatment and surgical prophylaxis.
Although mycophenolate is often used as second-line treatment for immune thrombocytopenia, its efficacy as first-line treatment in combination with corticosteroids is unknown.
Research presented at the 2020 annual meeting of the American Society of Hematology reveals semiautomatic densitometric analysis of von Willebrand factor multimers to have excellent accuracy in clinical practice.
Researchers evaluated coagulation-linked complications in critically ill patients with COVID-19 and survival outcomes following therapeutic anticoagulation.
Researchers compared quality of life and work-related function in patients with hemophilia A with patients with osteoarthritis and the general population.
Rurioctocog alfa pegol targeting FVIII troughs benefits patients with severe hemophilia A, according to research presented at the THSNA 2020 virtual meeting.
In expanded research, investigators studied the effects of therapeutic and prophylactic anticoagulation treatment in hospitalized patients with COVID-19.
Researchers studied the effect of certain biomarkers on long-term adverse cardiovascular outcomes in patients with coronary morbidities undergoing PCI.
Investigators studied the frequency and risk factors linked to wound healing complications after elective orthopedic surgery in patients with hemophilia.
A prospective, single-center study aimed to determine the prevalence of DVT after TKA among patients with hemophilia A and found that contrast-enhanced CT led to better detection compared with ultrasound.
In about 10% of pregnancies in which the mother has a congenital bleeding disorder, recommended fetal precautionary measures may influence the mode of delivery.
