Current State and Future Directions for Treating NPM1-Mutated Acute Myeloid Leukemia
Investigators addressed challenges associated with the biology, diagnosis, and current state of treatment for patients with NPM1-mutated AML.
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Current Treatment Options for Nodular Lymphocyte-Predominant Hodgkin Lymphoma
Investigators summarize current literature surrounding the treatment of NLPHL and discuss treatment considerations for 2 clinical cases.
Prepare for the End of Pandemic Telehealth Waivers
Healthcare providers should take steps now to ensure that the telehealth modalities they use are HIPAA compliant.
Treatment of Thrombotic Thrombocytopenic Purpura in Pregnancy
A pair of researchers discuss the treatment and specific clinical challenges associated with thrombotic thrombocytopenic purpura in women who are pregnant.
Multicenter Study of Spanish Patients Provides New Insights on COVID-19 in Multiple Myeloma
In addition to age, sex, and comorbidities, a new study flagged uncontrolled cancer and renal insufficiency as key prognostic factors for COVID-19 outcomes.
Polycythemia Vera and Essential Thrombocythemia: Diagnosis, Risk-Stratification, Management Updates
Investigators summarized current literature surrounding the diagnosis and risk-stratification of PV and ET, and reviewed available and upcoming therapies.
What Does Radiation Do to Organs at Risk in Patients With Lymphoma?
Depending on the type and stage of lymphoma, physicians may choose to avoid having their patients undergo radiation therapy for fear of potential toxic effects in organs.
ASH 2020 Guidelines on Venous Thromboembolism Management
The American Society of Hematology released evidence-based guidelines for the treatment of DVT and PE in patients without cancer.
Why It’s Been So Hard to Conclusively Link Environmental Factors to Non-Hodgkin Lymphoma
Small studies, the absence of subtypes, and a historical lack of genetic information has stopped past studies from triggering meaningful public health change, a review asserts.
British Society of Haematology Issues Updated Guidelines for Irradiated Blood Components
The British Society of Hematology has updated their guidelines on the use of irradiated blood components.
British Society for Haematology Guideline Update for the Diagnosis and Management of Chronic Myeloid Leukemia
The British Society for Haematology has published updated guidelines for the diagnosis and management of chronic myeloid leukemia in adults and children.
Maternal, Fetal Considerations for the Treatment and Management of Lymphoma During Pregnancy
Although 1 in 1000 lymphoma diagnoses occurs in pregnancy, literature on best practices for treatment in this patient group is limited.
Most Coronavirus-Positive Cancer Patients Are Asymptomatic, Says Study
An analysis showed that outcomes of SARS-CoV-2 infections can be disproportionately mild in some patient cohorts.
Thrombotic Thrombocytopenic Purpura: Expert Recommendations, Good Practice Statements for Critical Care
TTP is a rare disease that clinicians may not often treat; however, it is important to be aware of new developments for the treatment of this patient population.
New Analysis of the Tumor Microenvironment Reveals 3 Subtypes in Large B-Cell Lymphoma of the Brain
The signaling pathways detected may shed light on new treatment strategies.
2020 Guidelines on Treating Acute Myeloid Leukemia in Older Adults
Recent guidelines have provided additional information on the treatment, management, and risk-stratifications of acute myeloid leukemia in older patients.
How Doctors Can Cope With Psychological Distress During the Pandemic
When talking about work issues, Dr Bernstein recommends trying not to focus too much on how awful things are because it can be disheartening.
Diagnosis, Risk-Stratification, Management Updates in Myelodysplastic Syndromes
An overview of the diagnosis and management of MDS, including recent treatment, was discussed in a paper published in the American Journal of Hematology.
Triple Therapy for CLL Shows Promise in Phase 2 Trial
Most patients achieved deep remission after a 14-month regimen of obinutuzumab, ibrutinib, and venetoclax.
Communicating With Patients in Oncology About Care During the COVID-19 Pandemic
How to explain adjustments to cancer care due to the COVID-19 pandemic and ease patients’ fears about the impact of those changes.
Hepatosplenic T-cell Lymphoma: Recent Progress and Future Considerations
Researchers reviewed the clinical/pathologic aspects of HSTCL and summarized the latest molecular studies and potential novel therapeutic targets.
IT Asset Inventories Are a First Step in Securing Health Information
Practices need to know all of the components of their health information systems to determine potential vulnerabilities.
A New Hope for IL-18 Therapy
Engineered cytokine evades the tumor’s defenses and boosts the production of stem-like polyfunctional T cells.
Phase 1 Trial Featuring First shRNA-Edited CAR-T Therapy to Begin
FDA approves allogenic CAR T cells targeted at BCMA for phase 1 trial in relapsed/refractory multiple myeloma.
Targeted Molecular Therapies for the Treatment of Chronic Lymphocytic Leukemia
Researchers reviewed promising advances in therapy options for patients with CLL and the challenges associated with these new treatments.
Targeted Therapy for Non-Hodgkin Lymphoma: Current Progress and Future Plans
Novel immunotherapies and small molecule pathway inhibitors are transforming the standard of care for some of the most challenging lymphoma subtypes.
Clonal Hematopoiesis in Hematologic Malignancies, Bone Marrow Failure Syndromes, and Stem Cell Clones
Recent studies have better elucidated the link between clonal hematopoiesis and hematologic malignancies.
The Psychology of Collecting Debt: How to Get Patients to Pay Their Bills
By connecting on a personal level, medical practices may have better results in getting patients to settle their accounts.
Expert Q&A: Understanding the Oncogenic Role of HIV in Burkitt Lymphoma
While the rate of certain HIV-linked non-Hodgkin lymphomas has declined since the introduction of ART, the incidence of Burkitt lymphoma has remained steady.
The Twitter Effect on How Oncologists Conduct and Share Research
The social media platform can be useful as an education tool for oncologists to stay up to date on new research in oncology — but physicians still need to be mindful of the information sources.
G-CSF Appears Safe in CAR-T–Treated Patients With Refractory/Relapsed B-Cell Lymphoma
The treatment reduced hospital stay but not neutropenia duration or infection rate.
Pyruvate Kinase Deficiency: Current and Prospective Treatment Options
As PKD directly affects the catalysis of substrates and products involved in the production of ATP, the glycolytic pathway is compromised, thus leading to several cellular defects.
Incorporating Immunotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia
Immunotherapy is changing the treatment paradigm for pediatric patients with relapsed acute lymphoblastic leukemia.
Protecting Practices From Ransomware
Hackers have penetrated healthcare providers’ computer systems to encrypt information and demand money for its release.
How Patients Lose Their Own Voices: Disparities in Patient-Reported Outcome Capture in Clinical Trials
It remains important to interrogate how structural discrimination influences the collection of patient-reported outcomes.
Treatment Considerations for Thalassemia in the Emergency Department
Antoine N. Saliba, MD, and colleagues summarized current literature surrounding the frequent complications that bring patients with thalassemia into the ED.
New Class of Drug Appears to Extend Survival in Patients With Triple-Refractory Multiple Myeloma
Oncopeptides will seek accelerated approval from the FDA after melflufen demonstrates a manageable safety profile.
Prepare to E-Prescribe Controlled Substances
Beginning January 1, 2021, a federal law called the Every Prescription Conveyed Securely Act takes effect requiring that prescriptions for controlled substances covered under Medicare be prescribed electronically.
ASH 2020 Guidelines: Management of Acute and Chronic Pain in Sickle Cell Disease
The American Society of Hematology released their evidence-based 2020 guidelines on the management of acute and chronic pain in sickle cell disease.
Recognizing Hearing Loss in Elderly Patients
Communication breakdowns associated with a loss of hearing can potentially impact older patients’ adherence to treatment plans.
Examining Progress and Future Directions in Follicular Lymphoma Treatment
Researchers examine how far follicular lymphoma treatment has come, what limitations still remain, and where the management of the disease is headed.
Keeping Health Information Secure in the Cloud
Putting information in the cloud can be a good move for a physician’s practice — but only if done well.
Seven Tips for Managing Healthcare Teamwork During a Pandemic
COVID-19 has brought unprecedented stress to society at large and perhaps most of all to frontline healthcare teams in a variety of settings. We spoke to an expert about teamwork during such trying times.
Cancer and Fibromyalgia: Addressing the Needs of Patients Despite Limited Research
In addition to being common yet serious diseases, both cancer and fibromyalgia bring a high burden of physical pain and negative effects on mental health.
Diagnosing and Managing Patients With Primary Pancreatic Lymphoma
Because primary pancreatic lymphoma is a rare disease, optimal diagnostic and therapeutic protocols have not yet been established.
Why Cancer Centers May Need to Rethink the Hard Sell to Patients
Two recent papers are encouraging cancer center executives to rethink how they position their services to potential patients.
BSH Guideline Update for Assays Used in Hemostasis and Thrombosis
The British Society of Haematology released updates to 2 previous guidelines to help clinical laboratories with assays for coagulant diagnostic services.
Antibody-Drug Conjugates: Cancer Therapies to Watch
There are up to 80 ADCs in clinical development with close to 600 ongoing trials.
Functional Status May Predict Outcomes in Hospitalized Patients With Advanced Cancer
The association between functional impairment and symptom burden was shown to be predictive of outcomes for older patients with advanced cancer.
Explaining Treatment Risks to Patients
Physicians should frame treatment options by their “harms and benefits,” not by their “risks and benefits.”
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