Atrial fibrillation (AF) is a prevalent abnormal heart rhythm that can lead to severe complications such as stroke, major bleeding, heart failure, and death. The chances of developing AF may be increased in patients with cancer and could reflect a worse prognosis. Because evidence-based treatment guidelines for patients with AF and cancer are currently not…
Researchers recommended performing lactate dehydrogenase level and blood smear testing in patients with renal and neurological symptoms.
Different fusion genes of BCR-ABL1 are all leukemogenic for acute lymphoblastic leukemia or chronic myeloid leukemia (CML). According to results published in Leukemia, the particular transcripts present in patients with CML are correlated with sex and age and are not constant worldwide. This study systematically assessed the frequency of these leukemogenic fusion genes in patients…
Identifying patients with smoldering myeloma at high risk for disease progression may allow for implementation of better treatment strategies.
Results from a phase 3 open label trial (ClinicalTrials.gov Identifier: NCT01413178) published in The Lancet Haematology suggest that busulfan plus melphalan may result in longer progression-free survival (PFS) compared with melphalan alone in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplantation (HSCT). Patients with newly diagnosed multiple myeloma were accepted into the study…
Patients who developed cerebrovascular disease following allogeneic hematopoietic stem cell transplantation experienced decreased survival.
Patients’ responses to surveys assessing quality of life indicated impairment in both adults and adolescents.
Proteasome inhibitors and immunomodulatory drugs have demonstrated improvements in survival and response in patients with multiple myeloma.
Patients with severe sickle cell disease were more than twice as likely to experience recurrent thromboembolism compared with patients with less severe disease.
Patients receiving idelalisib experienced longer median overall survival compared with patients receiving placebo.
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