Anemias:
Indications for: TRIFERIC
Iron replacement to maintain hemoglobin in adults with hemodialysis-dependent chronic kidney disease (HDD-CKD).
Limitations of Use:
Not for use in patients receiving peritoneal dialysis. Not studied in patients receiving home hemodialysis.
Adult Dosage:
See full labeling. Must add soln (5mL or 50mL amp) or pwd (1 pkt) to bicarbonate concentrate (2.5 or 25gallons) for generation of hemodialysate. Final concentration (Triferic/in hemodialysate): 2micromolar (100mcg/L). Administer at each dialysis procedure.
Children Dosage:
Not established.
TRIFERIC Warnings/Precautions:
Monitor for hypersensitivity reactions during and after hemodialysis until clinically stable. Have personnel and resuscitative equipment immediately available. Determine iron status on pre-dialysis blood samples. Pregnancy. Advise females of reproductive potential to use effective contraception during and for at least 2weeks after therapy completion. Nursing mothers.
See Also:
TRIFERIC Classification:
Hematinic.
Adverse Reactions:
Headache, peripheral edema, asthenia, AV fistula thrombosis, urinary tract infection, AV fistula site hemorrhage, pyrexia, fatigue, procedural hypotension, muscle spasms, pain in extremity, back pain, dyspnea.
Generic Drug Availability:
NO
How Supplied:
Ampules (5mL)—5, 40; (50mL)—4, 24; Single-dose ampules (4.5mL)—10, 40; Packets— 1, 100
