Indications for: TRIFERIC

Iron replacement to maintain hemoglobin in adults with hemodialysis-dependent chronic kidney disease (HDD-CKD).

Limitations of Use:

Not for use in patients receiving peritoneal dialysis. Not studied in patients receiving home hemodialysis.

Adult Dosage:

See full labeling. Must add soln (5mL or 50mL amp) or pwd (1 pkt) to bicarbonate concentrate (2.5 or 25gallons) for generation of hemodialysate. Final concentration (Triferic/in hemodialysate): 2micromolar (100mcg/L). Administer at each dialysis procedure.

Children Dosage:

Not established.

TRIFERIC Warnings/Precautions:

Monitor for hypersensitivity reactions during and after hemodialysis until clinically stable. Have personnel and resuscitative equipment immediately available. Determine iron status on pre-dialysis blood samples. Pregnancy. Advise females of reproductive potential to use effective contraception during and for at least 2weeks after therapy completion. Nursing mothers.

See Also:

TRIFERIC Classification:


Adverse Reactions:

Headache, peripheral edema, asthenia, AV fistula thrombosis, urinary tract infection, AV fistula site hemorrhage, pyrexia, fatigue, procedural hypotension, muscle spasms, pain in extremity, back pain, dyspnea.

Generic Drug Availability:


How Supplied:

Ampules (5mL)—5, 40; (50mL)—4, 24; Single-dose ampules (4.5mL)—10, 40; Packets— 1, 100