Angina:
Indications for: TENORMIN
Long-term management of angina.
Adult Dosage:
Initially 50mg once daily. May increase after 1 week to 100mg daily; max 200mg/day. Elderly or renal impairment: may need lower dose; monitor trough BP. Coincide a dose for the end of hemodialysis.
Children Dosage:
Not established.
TENORMIN Contraindications:
Sinus bradycardia. 2nd- or 3rd-degree heart block. Overt heart failure. Cardiogenic shock.
Boxed Warning:
Cessation of therapy.
TENORMIN Warnings/Precautions:
Bronchospastic disease. Renal dysfunction. Diabetes. Hyperthyroidism. Pheochromocytoma. Surgery. Avoid abrupt cessation. Peripheral circulatory disorders. Ischemic heart disease or failure. Pregnancy (Cat.D): not recommended. Nursing mothers.
TENORMIN Classification:
Cardioselective beta-blocker.
TENORMIN Interactions:
Additive effect with catecholamine-depleting drugs, prazosin, digoxin. Conduction abnormalities, bradycardia, heart block with calcium channel blockers (esp. verapamil, diltiazem). Increased rebound hypertension with clonidine withdrawal. May block epinephrine.
Adverse Reactions:
Heart failure, bronchospasm, bradycardia, angina, MI, heart block, dizziness, fatigue, GI upset, depression, orthostatic hypotension, cold extremities.
How Supplied:
Tabs 25mg, 100mg—100; 50mg—100, 1000
Hypertension:
Indications for: TENORMIN
Hypertension.
Adult Dosage:
Initially 50mg daily. May increase after 1–2 weeks to 100mg once daily; max 100mg/day. Elderly: Initially 25–50mg daily; monitor trough BP. CrCl 15–35mL/minute: max 50mg/day; CrCl <15mL/minute: max 25mg/day; monitor trough BP. Coincide a dose for the end of hemodialysis.
Children Dosage:
Not established.
TENORMIN Contraindications:
Sinus bradycardia. 2nd- or 3rd-degree heart block. Overt heart failure. Cardiogenic shock.
Boxed Warning:
Cessation of therapy.
TENORMIN Warnings/Precautions:
Bronchospastic disease. Renal dysfunction. Diabetes. Hyperthyroidism. Pheochromocytoma. Surgery. Avoid abrupt cessation. Peripheral circulatory disorders. Ischemic heart disease or failure. Pregnancy (Cat.D): not recommended. Nursing mothers.
TENORMIN Classification:
Cardioselective beta-blocker.
TENORMIN Interactions:
Additive effect with catecholamine-depleting drugs, prazosin, digoxin. Conduction abnormalities, bradycardia, heart block with calcium channel blockers (esp. verapamil, diltiazem). Increased rebound hypertension with clonidine withdrawal. May block epinephrine.
Adverse Reactions:
Heart failure, bronchospasm, bradycardia, angina, MI, heart block, dizziness, fatigue, GI upset, depression, orthostatic hypotension, cold extremities.
How Supplied:
Tabs 25mg, 100mg—100; 50mg—100, 1000
