Gout:

Indications for: GLOPERBA

Prophylaxis of gout flares.

Limitations of Use:

Not studied for acute treatment of gout flares during prophylaxis. Not for treating pain from other causes.

Adult Dosage:

0.6mg (5mL) once or twice daily; max 1.2mg/day.

Children Dosage:

Not established.

GLOPERBA Contraindications:

Renal or hepatic impairment with concomitant CYP3A4 and P-gp dual inhibitors (life-threatening toxicity possible). Concurrent renal and hepatic impairment.

GLOPERBA Warnings/Precautions:

Monitor for toxicity; if present, consider temporary interruption or discontinuation. Renal or hepatic impairment. Elderly. Pregnancy. Nursing mothers.

GLOPERBA Classification:

Antiinflammatory.

GLOPERBA Interactions:

See Contraindications. Avoid concomitant CYP3A4 inhibitors (eg, clarithromycin, ketoconazole, grapefruit juice, erythromycin, verapamil) and/or P-gp inhibitors (eg, clarithromycin, ketoconazole, cyclosporine); if unavoidable, reduce daily dose or frequency, and monitor for colchicine toxicity. Concomitant statins or fibrates may potentiate myopathy. Concomitant posaconazole: max Gloperba 0.24mg (2mL).

Adverse Reactions:

Diarrhea, nausea, vomiting, abdominal pain; blood dyscrasias, neuromuscular toxicity, rhabdomyolysis, overdosage (may be fatal).

Generic Drug Availability:

NO

How Supplied:

Oral soln—150mL

Pricing for GLOPERBA

150ml of 0.6mg/5ml bottle of oral solution (Qty: 1)
Appx. price $343
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