Bleeding disorders:
Indications for: AMICAR TABLETS
Bleeding associated with fibrinolysis.
Adult Dosage:
Initially 5g during 1st hour, then 1g/hour for 8 hours or until bleeding is controlled.
Children Dosage:
Not recommended.
AMICAR TABLETS Contraindications:
Active intravascular clotting process. Disseminated intravascular coagulation without concomitant heparin.
AMICAR TABLETS Warnings/Precautions:
Upper urinary tract bleeding: not recommended. Cardiac, hepatic or renal disease. Risk of myopathy with long-term use; monitor creatine phosphokinase (CPK); discontinue if CPK rises. Avoid rapid IV administration. Neonates. Pregnancy (Cat.C). Nursing mothers.
See Also:
AMICAR TABLETS Classification:
Hemostatic.
AMICAR TABLETS Interactions:
Avoid concomitant Factor IX complex or Anti-inhibitor Coagulant concentrates; may increase thrombosis risk.
Adverse Reactions:
Bradycardia, hypotension, GI upset, edema, headache, malaise, CNS effects, thrombosis, others; rare: myopathy.
Drug Elimination:
Renal excretion is the primary route of elimination. Terminal elimination half-life is approximately 2 hours.
Generic Drug Availability:
YES
How Supplied:
Tabs—30; Oral soln—236.5mL
