Patrick Gallagher, Author at Hematology Advisor

Patrick Gallagher

All articles by Patrick Gallagher

Hereditary elliptocytosis and hereditary pyropoikilocytosis

Hereditary elliptocytosis and hereditary pyropoikilocytosis What every physician needs to know about hereditary elliptocytosis and hereditary pyropoikilocytosis: Hereditary elliptocytosis (HE) is characterized by the presence of elliptical or oval erythrocytes on the blood films of affected individuals. The worldwide incidence of HE is estimated to be between one in 2,000 and one in 4,000 individuals.…

Hereditary spherocytosis

Hereditary spherocytosis What every physician needs to know: Hereditary spherocytosis (HS) refers to a group of disorders characterized by spherical, doughnut-shaped erythrocytes with increased osmotic fragility. The clinical manifestations of the spherocytosis syndromes vary widely. The typical clinical picture of HS combines signs and symptoms of hemolysis (anemia, jaundice, reticulocytosis, gallstones, splenomegaly) with spherocytosis (spherocytes…

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