Megan Garlapow, PhD, Author at Hematology Advisor

Megan Garlapow, PhD

All articles by Megan Garlapow, PhD

A closeup shot of a render of the DNA helix.

Rates of Transcript Variants in Chronic Myeloid Leukemia Associated With Sex and Age

Different fusion genes of BCR-ABL1 are all leukemogenic for acute lymphoblastic leukemia or chronic myeloid leukemia (CML). According to results published in Leukemia, the particular transcripts present in patients with CML are correlated with sex and age and are not constant worldwide. This study systematically assessed the frequency of these leukemogenic fusion genes in patients…

No Correlation Between SF3B1 Mutation in Myelodysplastic Syndrome and Overall Survival

Results from a systematic review and meta-analysis published in Critical Reviews in Oncology/Hematology indicated there was no association between mutations in SF3B1 and overall survival (OS) in patients with myelodysplastic syndrome (MDS). Mutations in the SF3B1 gene are the most common mutations in MDS, though the prognostic implications of these mutations are unclear. In this…

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