Assessing Children With Bleeding Symptoms: Coagulation Disorder or Abuse?
Several factors need to be considered when determining whether a child’s bleeding symptoms are the result of a coagulation disorder, physical abuse, or both.
All articles by Lauren Dembeck, PhD
Vancomycin-Resistant Enterococcal Bacteremia Linked to Increased Mortality After HSCT
Vancomycin-resistant Enterococcus bacteremia was associated with poorer outcomes in patients undergoing allogeneic hematopoietic stem cell transplantation.
Pediatric Treatment Regimens for Older Adolescents and Young Adults With Acute Lymphoblastic Leukemia
According to a study published in Blood, using a pediatric regimen for patients up to 40 years of age with acute lymphoblastic leukemia (ALL) may improve survival rates compared with historical controls. The prospective study (CALGB 10403; ClinicalTrials.gov Identifier: NCT00558519) took place from 2007 to 2012 and used the same treatment doses and schedule as…
Pediatric Treatment Regimens for Older Adolescents and Young Adults With Acute Lymphoblastic Leukemia
Treating young adults with acute lymphoblastic leukemia with a pediatric regimen may lead to improved overall, event-free, and disease-free survival.
Antithrombin Deficiency May Be Undertreated With Standard Heparin Therapy
Antifactor Xa activity after heparin spiking was lower in plasma samples from antithrombin-deficient patients compared with control samples.
Pharmacokinetics-Based Hemophilia A Prophylaxis May Improve Clinical Outcomes
Researchers assessed the influence of adopting population pharmacokinetics to inform prophylaxis for patients with hemophilia A.
Comparing Decitabine Administration Schedules for the Treatment of Acute Myeloid Leukemia
Safety and efficacy did not differ significantly between 2 decitabine treatment schedules for acute myeloid leukemia.
Updates to Transfusion Strategies for Major Hemorrhage in Trauma
Changes in clinical management of trauma hemorrhage have significantly reduced mortality rates, but variation in treatment strategies still remains.
Erythropoietin-Stimulating Agents for the Treatment of Myelodysplastic Syndrome-Associated Anemia
A systematic literature review showed that erythropoietin-stimulating agents positively influenced outcomes of patients with MDS-associated anemia.
Novel Risk Score for Progression of Rhinovirus Infection in Hematopoietic Cell Transplantation Recipients
The risk factors of human rhinovirus lower respiratory tract infection following hematopoietic cell transplantation are not well known.
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