Nephrogenic Diabetes Insipidus
Diabetes insipidus (DI) is characterized by an inability to form a concentrated urine. This, in turn, causes the two most common symptoms, polyuria and polydipsia. The ability of the kidney to form a concentrated urine is dependent on adequate production and secretion of vasopressin (ADH) by the hypothalamic/pituitary axis and an intact collecting tubule vasopressin…
