Anti-CD117 CAR T Cells Promising Immunotherapeutic Modality for AML
Generating CAR T cells against human cognate receptor CD117 may be a successful treatment for patients with AML.
All articles by Jonathan Goodman, MPhil
Phase 2 Study of CPX-351 Results Promising in Relapsed Pediatric AML
Encouraging response rates in children with first relapse AML treated with CPX-351 followed by FLAG provide rationale for de novo AML study.
Prescription Drug Monitoring Programs May Prevent Patients With Cancer From Receiving Pain Management Therapy
Prescription drug monitoring programs that aim to prevent opioid misuse may be affecting patients with cancer who need pain management.
ETV6 Sequencing Important Among Patients With Inherited Thrombocytopenia, Malignancy
It may be important to sequence ETV6in patients with inherited thrombocytopenia or malignancy and to schedule regular follow-ups to check for secondary cancers.
Emapalumab Effective for Pediatric Primary Hemophagocytic Lymphohistiocytosis
Emapalumab as a target therapy may benefit children with primary HLH.
DOACs May Increase Risk of Bleeding Complications in Severe COVID-19 Cases
Replacing DOACs with alternative parenteral antithrombotic strategies may help to prevent bleeding complications in patients with SARS-CoV-2 infection.
Oxaliplatin May Reduce Nephrotoxicity Compared With Cisplatin in B-Cell Lymphoma
Researchers compared the efficacy and nephrotoxicity of R-DHAP vs R-DHAOx among patients treated for NHL between 2007 and 2014.
Autologous Stem Cell Transplantation Outcomes in Multiple Myeloma vs Non-Hodgkin Lymphoma
Higher graft CD34+ cell content is linked to improved platelet and neutrophil recovery after high-dose therapy.
SF3B1 Mutation in Clonal Cytopenia of Undetermined Significance Strongly Linked to Myelodysplastic Syndrome Development
Given the prevalence, the IWG-PM evaluated available evidence to determine whether SF3B1-mutated MDS should be recognized as a distinct disease subtype.
Imatinib as Potential Tyrosine Kinase Inhibitor to Treat Sickle Cell Disease
Although SCD is often linked to microvasculature occlusion, some sequelae are caused by erythrocyte membrane weakening.
