Jonathan Goodman, MPhil, Author at Hematology Advisor

A doctor explains a medication to an older patient.

Leukemia

Venetoclax With Chemotherapy: Promising for Elderly Patients With AML?

By

Jonathan Goodman, MPhil

August 6, 2020

Combined with chemotherapy, venetoclax appears to be effective for treating AML among fit elderly patients.

Lymphoma

Systematic Analysis Reveals Genomic Mutational Frequencies in MCL

By

Jonathan Goodman, MPhil

July 23, 2020

The authors noted that these findings should be seen as a reference for the mutational landscape in MCL at baseline and at disease progression after treatment.

Bleeding Disorders

Fetal Precautions Can Affect Mode of Delivery in Congenital Bleeding Disorders

By

Jonathan Goodman, MPhil

July 21, 2020

In about 10% of pregnancies in which the mother has a congenital bleeding disorder, recommended fetal precautionary measures may influence the mode of delivery.

Thrombotic Disorders

Caplacizumab Safe, Effective for Acquired Thrombotic Thrombocytopenic Purpura

By

Jonathan Goodman, MPhil

July 21, 2020

Caplacizumab appears to be safe and effective among patients with acquired thrombotic thrombocytopenic purpura treated in the real-world setting.

Anemia

Pre‐Implantation Genetic Diagnosis Effective for Sickle Cell Disease Transmission Prevention

By

Jonathan Goodman, MPhil

July 20, 2020

Couples that are at high risk of having offspring with SCD should be offered pre‐implantation genetic diagnosis treatment to prevent disease transmission.

Bone marrow biopsy from myelodysplastic condition under the microscope view. Histology tissue of bone marrow biopsy.

Myelodysplastic Syndromes

Premyelodysplastic Syndrome Blood Kinetics Linked to Survival, Disease Risk

By

Jonathan Goodman, MPhil

July 20, 2020

Premyelodysplastic syndrome blood kinetics are linked to both disease risk and overall survival.

Bleeding Disorders

Importance of Bleeding Phenotype, Diagnostic Trends in Congenital Platelet Defects

By

Jonathan Goodman, MPhil

July 7, 2020

There was a median bleeding score of 21 among patients with Glanzmann thrombasthenia, 9 in Bernard-Soulier syndrome, 10 in dense granule deficiency, 7 in ADP pathway defect, 8 in TxA2 pathway defect, 6 in isolated thrombocytopenia, and 8 in complex abnormalities.

General Hematology

Sedentary Behavior Linked With Greater Risk of Cancer-Related Mortality

By

Jonathan Goodman, MPhil

July 6, 2020

Prospective trials regarding sedentary lifestyles and all cause mortality using measurements more objective than self-reported activity are currently lacking.