NCCN Guidelines for Multiple Myeloma Updated to Include Three Selinexor Regimens
The National Comprehensive Cancer Network’s updated Clinical Practice Guidelines in Oncology for multiple myeloma newly include 3 new selinexor-containing regimens.
All articles by Caroline Seydel
Sodium Bicarbonate Associated With Enhanced GVL Effect in AML Following Allo-HSCT
Investigators assessed sodium bicarbonate’s viability as a pharmacologic strategy in mouse models and humans with acute myeloid leukemia.
Triple Therapy for CLL Shows Promise in Phase 2 Trial
Most patients achieved deep remission after a 14-month regimen of obinutuzumab, ibrutinib, and venetoclax.
A New Hope for IL-18 Therapy
Engineered cytokine evades the tumor’s defenses and boosts the production of stem-like polyfunctional T cells.
New Class of Drug Appears to Extend Survival in Patients With Triple-Refractory Multiple Myeloma
Oncopeptides will seek accelerated approval from the FDA after melflufen demonstrates a manageable safety profile.
Some Targeted Therapies May Miss the Mark
Ten different drugs continued to kill cancer cells even when their target proteins were removed.
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