Caleb Rans, PharmD

Contributing Writer https://www.hematologyadvisor.com

Caleb Rans is a clinical pharmacist and medical communications specialist with professional expertise in medical writing, editing, and contract clinical research. He holds a PharmD from the University of Alberta and presently resides in Vancouver, Canada. He currently works as an independent consultant for several news, CME, and pharmaceutical companies.

All articles by Caleb Rans, PharmD

Researchers are examining the role of platelets as drivers of inflammation, which may provide a mechanistic link with ischemia-reperfusion injury.

Thrombotic Disorders

Evaluating the Role of Platelets in Ischemia-Reperfusion Injury Post-Stroke

Caleb Rans, PharmD

April 9, 2021

Researchers are examining the role of platelets as drivers of inflammation, which may provide a mechanistic link with ischemia-reperfusion injury.

A study showed how long patients with CLL may live after CAR-T therapy failure, providing a benchmark for trials evaluating therapies in the post–CAR-T setting.

Leukemia

The Role of Early Intervention in the Treatment of Early-Stage CLL

Caleb Rans, PharmD

April 2, 2021

There is a need for further investigation of early intervention options for patients with early-stage CLL.

Researchers conducted a meta-analysis of 4 studies examining prophylaxis with factor VIII or emicizumab for hemophilia A without inhibitors.

Bleeding Disorders

Mild to Moderate Hemophilia: Experts Discuss Challenges and Propose Solutions

Caleb Rans, PharmD

February 26, 2021

A group of US-based hemophilia experts summarized unmet needs in mild to moderate hemophilia and provided suggestions for healthcare professionals to optimally manage their patients with this challenging condition.

Thrombotic Disorders

Current Treatment Options for Pregnancy-Related Venous Thromboembolism

Caleb Rans, PharmD

January 13, 2021

A recently published review outlines the approach to the treatment of venous thromboembolism in pregnancy using patient case studies from their clinical practice in a Netherlands-based academic hospital.

Leukemia

Hairy Cell Leukemia and Hairy Cell Variant: BSH Updates in Diagnosis and Management

Caleb Rans, PharmD

December 22, 2020

The British Society for Haematology released an updated guideline, listing recommendations for the diagnosis and management of hairy cell leukemia and hairy cell variant.

A new study reveals that an aging world population is the predominant contributor to a 126% increase

Lymphoma

Current Treatment Options for Nodular Lymphocyte-Predominant Hodgkin Lymphoma

Caleb Rans, PharmD

November 24, 2020

Investigators summarize current literature surrounding the treatment of NLPHL and discuss treatment considerations for 2 clinical cases.

General Hematology

Polycythemia Vera and Essential Thrombocythemia: Diagnosis, Risk-Stratification, Management Updates

Caleb Rans, PharmD

November 11, 2020

Investigators summarized current literature surrounding the diagnosis and risk-stratification of PV and ET, and reviewed available and upcoming therapies.

A doctor sits at his desk, working hard.

Leukemia

British Society for Haematology Guideline Update for the Diagnosis and Management of Chronic Myeloid Leukemia

Caleb Rans, PharmD

October 21, 2020

The British Society for Haematology has published updated guidelines for the diagnosis and management of chronic myeloid leukemia in adults and children.

General Hematology

Clonal Hematopoiesis in Hematologic Malignancies, Bone Marrow Failure Syndromes, and Stem Cell Clones

Caleb Rans, PharmD

September 2, 2020

Recent studies have better elucidated the link between clonal hematopoiesis and hematologic malignancies.

General Hematology

Pyruvate Kinase Deficiency: Current and Prospective Treatment Options

Caleb Rans, PharmD

August 19, 2020

As PKD directly affects the catalysis of substrates and products involved in the production of ATP, the glycolytic pathway is compromised, thus leading to several cellular defects.

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