Caleb Rans, PharmD

Contributing Writer https://www.hematologyadvisor.com

Caleb Rans is a clinical pharmacist and medical communications specialist with professional expertise in medical writing, editing, and contract clinical research. He holds a PharmD from the University of Alberta and presently resides in Vancouver, Canada. He currently works as an independent consultant for several news, CME, and pharmaceutical companies.

All articles by Caleb Rans, PharmD

General Hematology

Clonal Hematopoiesis in Hematologic Malignancies, Bone Marrow Failure Syndromes, and Stem Cell Clones

Caleb Rans, PharmD

September 2, 2020

Recent studies have better elucidated the link between clonal hematopoiesis and hematologic malignancies.

General Hematology

Pyruvate Kinase Deficiency: Current and Prospective Treatment Options

Caleb Rans, PharmD

August 19, 2020

As PKD directly affects the catalysis of substrates and products involved in the production of ATP, the glycolytic pathway is compromised, thus leading to several cellular defects.

Thalassemias

Treatment Considerations for Thalassemia in the Emergency Department

Caleb Rans, PharmD

August 5, 2020

Antoine N. Saliba, MD, and colleagues summarized current literature surrounding the frequent complications that bring patients with thalassemia into the ED.

Thrombotic Disorders

BSH Guideline Update for Assays Used in Hemostasis and Thrombosis

Caleb Rans, PharmD

July 8, 2020

The British Society of Haematology released updates to 2 previous guidelines to help clinical laboratories with assays for coagulant diagnostic services.

This fact sheet provides an overview of the updated ESMO clinical practice guideline for hereditary GI cancers.

General Hematology

New ASCO Clinical Guidelines on Management of Cancer Cachexia

Caleb Rans, PharmD

June 24, 2020

The American Society of Clinical Oncology published new clinical guidelines on the management of cachexia in adults with advanced cancer.

Anemia

ASH 2020 Clinical Guidelines: Sickle Cell Disease and Cerebrovascular Disease

Caleb Rans, PharmD

May 20, 2020

ASH published new clinical guidelines on the prevention, diagnosis, and treatment of CNS complications for children and adults with sickle cell disease.

To tweak CAR-T therapies for myeloma, researchers are trying to repurpose a failed Alzheimer’s drug and are extracting patients’ T cells sooner.

General Hematology

Toxicity Management in the Era of Novel Therapies for Hematologic Malignancies

Caleb Rans, PharmD

March 11, 2020

Researchers provided an overview of toxicities associated with the use of novel agents to treat hematologic malignancies, as well as potential management strategies.

A doctor shows a tablet to an elderly patient

Lymphoma

Current and Prospective Treatment Options for Waldenström Macroglobulinemia

Caleb Rans, PharmD

February 7, 2020

Researchers discussed diagnostic considerations, indications for therapy, and treatment options for patients with Waldenström macroglobulinemia.

General Hematology

Personalizing Intensive Therapy for Older Patients With Hematologic Cancers

Caleb Rans, PharmD

January 29, 2020

Several factors need to be considered when choosing optimal therapy for older patients with hematologic malignancies, particularly when it comes to managing toxicity.