Eculizumab May Be Safe in Pregnancy, But Data Are Limited

Eculizumab has been used to treat paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.

Latest News

Anemia May Be Associated With Increased Mortality and Length of Hospital Stay


More than one-third of nonanemic patients admitted to Royal Perth Hospital in Australia developed anemia during their stay.

Patients With Diamond-Blackfan Anemia May Be at Higher Risk for Certain Cancers


Researchers analyzed prospective follow-up data from 702 patients with Diamond-Blackfan anemia for cancer incidence and risk.

Management of Red Blood Cell Exchange in African American Patients With Sickle Cell Disease


Approximately 1 in 500 African Americans in the United States has sickle cell disease.

Anemia Identified as Risk Factor for Contrast-Induced Acute Kidney Injury

By Bryant Moeller

Anemia with a baseline hemoglobin <13 g/dL was associated with a more than 5-fold increased risk for contrast-induced acute kidney injury in patients undergoing coronary angiography.

FDA Approves Epoetin Alfa Biosimilar Retacrit

By Steve Duffy

The approval of Retacrit was based on a review of evidence that included human pharmacokinetic/pharmacodynamic data and clinical immunogenicity data which demonstrated a high degree of similarity between Retacrit and its reference product.

Biomarker Indicates Brain Tissue at Risk for Stroke in Sickle Cell Disease

By Brandon May

Using the infarct heat map, the investigators determined that infarct density was higher in the deep white matter and co-localized with the elevated OEF region in the independent prospective cohort.

Anemia Associated With Radiographic Progression in Methotrexate-Naïve Patients

By Brandon May

In this post hoc analysis, researchers explored whether anemia was a predictor of radiographic progression in patients with RA who were treated with tofacitinib.

Aplastic Anemia Outcomes Examined for Anti-Thymoglobulin-Based IST

The researchers found that OS was superior in IST responders. Shorter relapse-free survival (RFS) was seen with partial response to IST compared with complete response.

Tocilizumab Associated With Improved Anemia Markers in Patients With Rheumatoid Arthritis

By Cindy Lampner, MSLIS

Other biologic DMARDs were not associated with any significant clinically meaningful increase in Hb and Hct levels.

Coronary Artery Disease Mortality Predicted by Anemia

By Steve Duffy

Low hemoglobin levels independently predicted all-cause, cardiovascular, and noncardiovascular mortality in patients with coronary artery disease.

Sickle Cells Disease Patients Have Unique Cardiomyopathy with Restrictive Physiology

By Lauren Grygotis

Patients with sickle cell disease may have a unique cardiomyopathy with restrictive physiology.

Lipids, Vitamin B12, Folate Affected by Iron Deficiency Anemia

Treatment of iron deficiency anemia was linked to improvements in vitamin B12, folate and lipids.