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Thrombotic Disorders

Management of Venous Thrombosis in Unusual Sites

The incidence, pathophysiology, provoking factors, and recommended treatments for several types of unusual thrombosis were summarized in a review article.

Bleeding Disorders

Andexanet Alfa and the Role of Reversal Agents for Factor Xa Inhibitors

Andexanet alfa is the first anticoagulant reversal agent to receive global US FDA approval for patients with life-threatening or uncontrolled bleeding.

Leukemia

A New Genomic Dataset May be a Significant Step Forward in Combating Acute Myeloid Leukemia

A dataset comprising 672 tumor specimens collected from 562 patients describes both genetic and functional information about the biology of AML.

Thrombotic Disorders

The Role of Viral Infections and Vaccines in the Pathogenesis of Antiphospholipid Syndrome

By Helen Fosam

Recent evidence links specific bacterial, viral infections, and vaccination to the development of APS, but these associations are not clear-cut.

Anemia

Eculizumab May Be Safe in Pregnancy, But Data Are Limited

Eculizumab has been used to treat paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome.

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